Literature summary extracted from

Russell, J.J.; Patel, M.S.
Purification and properties of succinyl-CoA:3-oxo-acid CoA-transferase from rat brain (1982), J. Neurochem., 38, 1446-1452.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.8.3.5	acetoacetate	substrate inhibition above 1 mM	Rattus norvegicus

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
2.8.3.5	0.025	-	succinate	cosusbstrate: acetoacetyl-CoA	Rattus norvegicus
2.8.3.5	0.059	-	acetoacetyl-CoA	cosusbstrate: succinate	Rattus norvegicus
2.8.3.5	0.07	-	acetoacetate	cosusbstrate: succinyl-CoA	Rattus norvegicus
2.8.3.5	0.156	-	succinyl-CoA	cosusbstrate: acetoacetate	Rattus norvegicus

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
2.8.3.5	mitochondrion	-	Rattus norvegicus	5739	-

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
2.8.3.5	53000	-	2 * 53000, SDS-PAGE	Rattus norvegicus
2.8.3.5	90000	-	gel filtration	Rattus norvegicus

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.8.3.5	Rattus norvegicus	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
2.8.3.5	-	Rattus norvegicus

Reaction

EC Number	Reaction	Comment	Organism	Reaction ID
2.8.3.5	succinyl-CoA + a 3-oxo acid = succinate + a 3-oxoacyl-CoA	mechanism	Rattus norvegicus	a

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.8.3.5	brain	-	Rattus norvegicus	-

Specific Activity [micromol/min/mg]

EC Number	Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
2.8.3.5	161	-	-	Rattus norvegicus

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.8.3.5	succinyl-CoA + acetoacetate	-	Rattus norvegicus	succinate + acetoacetyl-CoA	-	r

Subunits

EC Number	Subunits	Comment	Organism
2.8.3.5	dimer	2 * 53000, SDS-PAGE	Rattus norvegicus

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Release 2023.1 (January 2023)