EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.8.1.6 | Iron | in a partially purified fraction the presence of a S2- source and Fe2+ converts the predominant [2Fe-2S] into a 1:1 mixture of [2Fe-2S] and [4Fe-4S], reduced [4Fe-4S] is involved in mediating the cleavage of S-adenosylmethionine and reduced [2Fe-2S] is the sulfur source of biotin | Escherichia coli | |
2.8.1.6 | Iron | presence of a [2Fe-2S] cluster | Escherichia coli |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.8.1.6 | dethiobiotin + sulfur | Escherichia coli | catalyzes the last step of the biosynthesis of biotin | biotin | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.8.1.6 | Escherichia coli | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.8.1.6 | - |
Escherichia coli |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
2.8.1.6 | dethiobiotin + sulfur-(sulfur carrier) + 2 S-adenosyl-L-methionine + 2 reduced [2Fe-2S] ferredoxin = biotin + (sulfur carrier) + 2 L-methionine + 2 5'-deoxyadenosine + 2 oxidized [2Fe-2S] ferredoxin | mechanism | Escherichia coli |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.8.1.6 | dethiobiotin + sulfur | - |
Escherichia coli | biotin | - |
? | |
2.8.1.6 | dethiobiotin + sulfur | catalyzes the last step of the biosynthesis of biotin | Escherichia coli | biotin | - |
? |