EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.8.1.6 | FeCl3 | - |
Escherichia coli | |
2.8.1.6 | FeCl3 | enhances activity 3-4fold at 0.1 mM | Lysinibacillus sphaericus | |
2.8.1.6 | Iron | the enzyme contains an iron-sulfur cluster | Escherichia coli | |
2.8.1.6 | Iron | the enzyme contains an iron-sulfur cluster | Lysinibacillus sphaericus | |
2.8.1.6 | Na2S | - |
Escherichia coli | |
2.8.1.6 | Na2S | enhances activity 3-4fold at 1 mM | Lysinibacillus sphaericus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.8.1.6 | dethiobiotin + sulfur | Escherichia coli | hypothesis: sulfur of biotin is derived from the [Fe-S] center of the enzyme | biotin | - |
? | |
2.8.1.6 | dethiobiotin + sulfur | Lysinibacillus sphaericus | hypothesis: sulfur of biotin is derived from the [Fe-S] center of the enzyme | biotin | - |
? | |
2.8.1.6 | dethiobiotin + sulfur | Escherichia coli | catalyzes the last step of the biosynthesis of biotin | biotin | - |
? | |
2.8.1.6 | dethiobiotin + sulfur | Lysinibacillus sphaericus | catalyzes the last step of the biosynthesis of biotin | biotin | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.8.1.6 | Escherichia coli | - |
- |
- |
2.8.1.6 | Lysinibacillus sphaericus | - |
- |
- |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
2.8.1.6 | dethiobiotin + sulfur-(sulfur carrier) + 2 S-adenosyl-L-methionine + 2 reduced [2Fe-2S] ferredoxin = biotin + (sulfur carrier) + 2 L-methionine + 2 5'-deoxyadenosine + 2 oxidized [2Fe-2S] ferredoxin | mechanism | Escherichia coli | |
2.8.1.6 | dethiobiotin + sulfur-(sulfur carrier) + 2 S-adenosyl-L-methionine + 2 reduced [2Fe-2S] ferredoxin = biotin + (sulfur carrier) + 2 L-methionine + 2 5'-deoxyadenosine + 2 oxidized [2Fe-2S] ferredoxin | mechanism | Lysinibacillus sphaericus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.8.1.6 | dethiobiotin + sulfur | - |
Escherichia coli | biotin | - |
? | |
2.8.1.6 | dethiobiotin + sulfur | - |
Lysinibacillus sphaericus | biotin | - |
? | |
2.8.1.6 | dethiobiotin + sulfur | hypothesis: sulfur of biotin is derived from the [Fe-S] center of the enzyme | Escherichia coli | biotin | - |
? | |
2.8.1.6 | dethiobiotin + sulfur | hypothesis: sulfur of biotin is derived from the [Fe-S] center of the enzyme | Lysinibacillus sphaericus | biotin | - |
? | |
2.8.1.6 | dethiobiotin + sulfur | catalyzes the last step of the biosynthesis of biotin | Escherichia coli | biotin | - |
? | |
2.8.1.6 | dethiobiotin + sulfur | catalyzes the last step of the biosynthesis of biotin | Lysinibacillus sphaericus | biotin | - |
? |