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Literature summary extracted from

  • terentyev, L.L.; Terentyeva, N.A.; Rasskazov, V.A.
    Purification and some properties of thymidylate kinase from sea urchin (1999), Biochemistry, 64, 80-85.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.4.9 Cu2+
-
 Strongylocentrotus intermedius
2.7.4.9 Fe2+
-
 Strongylocentrotus intermedius
2.7.4.9 Zn2+
-
 Strongylocentrotus intermedius

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.4.9 Ca2+ can partially replace Mg2+ in activation Strongylocentrotus intermedius
2.7.4.9 Cd2+ can partially replace Mg2+ in activation Strongylocentrotus intermedius
2.7.4.9 Co2+ can partially replace Mg2+ in activation Strongylocentrotus intermedius
2.7.4.9 Mg2+ activity is maximal in presence of 2-5 mM ATP and 10 mM MgCl2 Strongylocentrotus intermedius
2.7.4.9 Mn2+ can partially replace Mg2+ in activation Strongylocentrotus intermedius

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.4.9 100000
-
-
 Strongylocentrotus intermedius

Organism

EC Number Organism UniProt Comment Textmining
2.7.4.9 Strongylocentrotus intermedius
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.4.9 egg
-
 Strongylocentrotus intermedius
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.4.9 ATP + dCMP
-
 Strongylocentrotus intermedius ADP + dCDP
-
 ?
2.7.4.9 ATP + dTMP
-
 Strongylocentrotus intermedius ADP + dTDP
-
 ?
2.7.4.9 dCTP + dTMP
-
 Strongylocentrotus intermedius dCDP + dTDP
-
 ?
2.7.4.9 dTTP + dTMP
-
 Strongylocentrotus intermedius dTDP
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.4.9 8 8.5
-
 Strongylocentrotus intermedius