BRENDA - Enzyme Database

Purification and some properties of thymidylate kinase from sea urchin

terentyev, L.L.; Terentyeva, N.A.; Rasskazov, V.A.; Biochemistry 64, 80-85 (1999)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
2.7.4.9
Cu2+
-
Strongylocentrotus intermedius
2.7.4.9
Fe2+
-
Strongylocentrotus intermedius
2.7.4.9
Zn2+
-
Strongylocentrotus intermedius
Metals/Ions
EC Number
Metals/Ions
Commentary
Organism
Structure
2.7.4.9
Ca2+
can partially replace Mg2+ in activation
Strongylocentrotus intermedius
2.7.4.9
Cd2+
can partially replace Mg2+ in activation
Strongylocentrotus intermedius
2.7.4.9
Co2+
can partially replace Mg2+ in activation
Strongylocentrotus intermedius
2.7.4.9
Mg2+
activity is maximal in presence of 2-5 mM ATP and 10 mM MgCl2
Strongylocentrotus intermedius
2.7.4.9
Mn2+
can partially replace Mg2+ in activation
Strongylocentrotus intermedius
Molecular Weight [Da]
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
2.7.4.9
100000
-
-
Strongylocentrotus intermedius
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.7.4.9
Strongylocentrotus intermedius
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.7.4.9
egg
-
Strongylocentrotus intermedius
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.4.9
ATP + dCMP
-
645205
Strongylocentrotus intermedius
ADP + dCDP
-
-
-
?
2.7.4.9
ATP + dTMP
-
645205
Strongylocentrotus intermedius
ADP + dTDP
-
-
-
?
2.7.4.9
dCTP + dTMP
-
645205
Strongylocentrotus intermedius
dCDP + dTDP
-
-
-
?
2.7.4.9
dTTP + dTMP
-
645205
Strongylocentrotus intermedius
dTDP
-
-
-
?
pH Optimum
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
2.7.4.9
8
8.5
-
Strongylocentrotus intermedius
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
2.7.4.9
Cu2+
-
Strongylocentrotus intermedius
2.7.4.9
Fe2+
-
Strongylocentrotus intermedius
2.7.4.9
Zn2+
-
Strongylocentrotus intermedius
Metals/Ions (protein specific)
EC Number
Metals/Ions
Commentary
Organism
Structure
2.7.4.9
Ca2+
can partially replace Mg2+ in activation
Strongylocentrotus intermedius
2.7.4.9
Cd2+
can partially replace Mg2+ in activation
Strongylocentrotus intermedius
2.7.4.9
Co2+
can partially replace Mg2+ in activation
Strongylocentrotus intermedius
2.7.4.9
Mg2+
activity is maximal in presence of 2-5 mM ATP and 10 mM MgCl2
Strongylocentrotus intermedius
2.7.4.9
Mn2+
can partially replace Mg2+ in activation
Strongylocentrotus intermedius
Molecular Weight [Da] (protein specific)
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
2.7.4.9
100000
-
-
Strongylocentrotus intermedius
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.7.4.9
egg
-
Strongylocentrotus intermedius
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.4.9
ATP + dCMP
-
645205
Strongylocentrotus intermedius
ADP + dCDP
-
-
-
?
2.7.4.9
ATP + dTMP
-
645205
Strongylocentrotus intermedius
ADP + dTDP
-
-
-
?
2.7.4.9
dCTP + dTMP
-
645205
Strongylocentrotus intermedius
dCDP + dTDP
-
-
-
?
2.7.4.9
dTTP + dTMP
-
645205
Strongylocentrotus intermedius
dTDP
-
-
-
?
pH Optimum (protein specific)
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
2.7.4.9
8
8.5
-
Strongylocentrotus intermedius