BRENDA - Enzyme Database

The Drosophila melanogaster UMP-CMP kinase cDNA encodes an N-terminal mitochondrial import signal

Curbo, S.; Amiri, M.; Foroogh, F.; Johansson, M.; Karlsson, A.; Biochem. Biophys. Res. Commun. 311, 440-445 (2003)

Data extracted from this reference:

Cloned(Commentary)
EC Number
Commentary
Organism
2.7.4.14
expression in Escherichia coli
Drosophila melanogaster
KM Value [mM]
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
2.7.4.14
0.017
-
dCMP
pH 8.0, 37C
Drosophila melanogaster
2.7.4.14
0.023
-
CMP
pH 8.0, 37C
Drosophila melanogaster
2.7.4.14
0.095
-
UMP
pH 8.0, 37C
Drosophila melanogaster
2.7.4.14
0.43
-
dUMP
pH 8.0, 37C
Drosophila melanogaster
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.7.4.14
mitochondrion
N-terminal signal targets the enzyme to mitochondria
Drosophila melanogaster
5739
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.7.4.14
Drosophila melanogaster
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.4.14
ATP + CMP
-
645155
Drosophila melanogaster
ADP + CDP
-
-
-
?
2.7.4.14
ATP + dCMP
-
645155
Drosophila melanogaster
ADP + dCDP
-
-
-
?
2.7.4.14
ATP + dUMP
-
645155
Drosophila melanogaster
ADP + dUDP
-
-
-
?
2.7.4.14
ATP + UMP
-
645155
Drosophila melanogaster
ADP + UDP
-
-
-
?
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
2.7.4.14
expression in Escherichia coli
Drosophila melanogaster
KM Value [mM] (protein specific)
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
2.7.4.14
0.017
-
dCMP
pH 8.0, 37C
Drosophila melanogaster
2.7.4.14
0.023
-
CMP
pH 8.0, 37C
Drosophila melanogaster
2.7.4.14
0.095
-
UMP
pH 8.0, 37C
Drosophila melanogaster
2.7.4.14
0.43
-
dUMP
pH 8.0, 37C
Drosophila melanogaster
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.7.4.14
mitochondrion
N-terminal signal targets the enzyme to mitochondria
Drosophila melanogaster
5739
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.4.14
ATP + CMP
-
645155
Drosophila melanogaster
ADP + CDP
-
-
-
?
2.7.4.14
ATP + dCMP
-
645155
Drosophila melanogaster
ADP + dCDP
-
-
-
?
2.7.4.14
ATP + dUMP
-
645155
Drosophila melanogaster
ADP + dUDP
-
-
-
?
2.7.4.14
ATP + UMP
-
645155
Drosophila melanogaster
ADP + UDP
-
-
-
?