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Literature summary extracted from

  • Anderson, E.P.
    UMP-CMP kinase from Tetrahymena pyriformis (1978), Methods Enzymol., 51, 331-337.
    View publication on PubMed

General Stability

EC Number General Stability Organism
2.7.4.14 three-fold dilution of a preparation of 0.2 mg of protein per ml results in less of 50% of the activity in 1 h Tetrahymena pyriformis

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.4.14 CDP competitive withCMP Tetrahymena pyriformis

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.4.14 0.5
-
 ATP
-
 Tetrahymena pyriformis
2.7.4.14 0.8
-
 CMP
-
 Tetrahymena pyriformis
2.7.4.14 1.25
-
 CMP
-
 Tetrahymena pyriformis

Organism

EC Number Organism UniProt Comment Textmining
2.7.4.14 Tetrahymena pyriformis
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.4.14
-
 Tetrahymena pyriformis

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.7.4.14 27.5
-
-
 Tetrahymena pyriformis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.4.14 ATP + CMP
-
 Tetrahymena pyriformis ADP + CDP
-
 ?
2.7.4.14 ATP + dCMP
-
 Tetrahymena pyriformis ADP + dCDP
-
 ?
2.7.4.14 ATP + UMP
-
 Tetrahymena pyriformis ADP + UDP
-
 ?
2.7.4.14 dATP + UMP dATP shows 10% of the activity with ATP Tetrahymena pyriformis dADP + ADP
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.4.14 7 8
-
 Tetrahymena pyriformis