EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.17 | DTT | enzyme is inactive in absence either EDTA or a thiol such as reduced monosodium glutathione or dithiothreitol | Klebsiella aerogenes | |
2.7.1.17 | EDTA | enzyme is inactive in absence either EDTA or a thiol such as reduced monosodium glutathione or dithiothreitol | Klebsiella aerogenes | |
2.7.1.17 | Monosodium glutathione | enzyme is inactive in absence either EDTA or a thiol such as reduced monosodium glutathione or dithiothreitol | Klebsiella aerogenes |
EC Number | General Stability | Organism |
---|---|---|
2.7.1.17 | D-xylulose, ATP, glycerol and EDTA stabilize | Klebsiella aerogenes |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.17 | Mg2+ | above 0.08 mM | Klebsiella aerogenes |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.17 | Mg2+ | MgCl2 required, optimal concentration: 0.05 mM | Klebsiella aerogenes | |
2.7.1.17 | Mn2+ | 90% as effective as Mg2+ in activation | Klebsiella aerogenes | |
2.7.1.17 | Ni2+ | activation, half as effective as Mg2+ | Klebsiella aerogenes |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.17 | ATP + D-xylulose | Klebsiella aerogenes | enzyme of ribitol catabolism, inducible by ribitol | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.1.17 | Klebsiella aerogenes | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.7.1.17 | - |
Klebsiella aerogenes |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.7.1.17 | 95 | - |
- |
Klebsiella aerogenes |
EC Number | Storage Stability | Organism |
---|---|---|
2.7.1.17 | -20°C, about 30% of original activity retained after 4 years | Klebsiella aerogenes |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.17 | ATP + D-xylulose | enzyme of ribitol catabolism, inducible by ribitol | Klebsiella aerogenes | ? | - |
? | |
2.7.1.17 | ATP + D-xylulose | specific for D-isomer | Klebsiella aerogenes | ADP + D-xylulose 5-phosphate | - |
r | |
2.7.1.17 | ATP + xylitol | poor substrate | Klebsiella aerogenes | ADP + ? | - |
? | |
2.7.1.17 | GTP + D-xylulose | phosphorylation at 25% the rate of ATP | Klebsiella aerogenes | GDP + D-xylulose 5-phosphate | - |
? | |
2.7.1.17 | ITP + D-xylulose | phosphorylation at 25% the rate of ATP | Klebsiella aerogenes | IDP + D-xylulose 5-phosphate | - |
? | |
2.7.1.17 | UTP + D-xylulose | phosphorylation at 14% the rate of ATP | Klebsiella aerogenes | UDP + D-xylulose 5-phosphate | - |
? |