EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.3.1.169 | CO | a cobalt-containing Co/Fe-S component of multienzyme complex serves as a methyl carrier in the pathway of methane synthesis from acetate | Moorella thermoacetica | |
2.3.1.169 | Fe | corrinoid/iron-sulfur protein required | Moorella thermoacetica |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.169 | additional information | Moorella thermoacetica | key enzyme in the autotrophic acetyl-CoA pathway, i.e. Wood pathway, enzyme catalyses the final steps in this pathway | ? | - |
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EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.1.169 | Moorella thermoacetica | - |
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EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
2.3.1.169 | acetyl-CoA + a [Co(I) corrinoid Fe-S protein] = CO + CoA + a [methyl-Co(III) corrinoid Fe-S protein] | the FeS cluster is present to relay electrons from enzyme to CO | Moorella thermoacetica | |
2.3.1.169 | acetyl-CoA + a [Co(I) corrinoid Fe-S protein] = CO + CoA + a [methyl-Co(III) corrinoid Fe-S protein] | the transfer of methyl group to enzyme occurs by SN2-type nucleophilic displacement, not a radical, reaction | Moorella thermoacetica |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.169 | CH3-tetrahydrofolate + CO + HS-CoA | - |
Moorella thermoacetica | CH3-CO-S-CoA + tetrahydrofolate | - |
? | |
2.3.1.169 | CO + methyl-X + HS-CoA | - |
Moorella thermoacetica | CH3-CO-S-CoA + HX | - |
? | |
2.3.1.169 | additional information | key enzyme in the autotrophic acetyl-CoA pathway, i.e. Wood pathway, enzyme catalyses the final steps in this pathway | Moorella thermoacetica | ? | - |
? |