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Literature summary extracted from

  • Kasmi, A.E.; Rajasekharan, S.; Ragsdale, S.W.
    Anaerobic pathway for conversion of the methyl group of aromatic methyl ethers to acetic acid by Clostridium thermoaceticum (1994), Biochemistry, 33, 11217-11224.
    View publication on PubMed

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.3.1.169 Fe corrinoid/iron-sulfur protein required Moorella thermoacetica

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.169 additional information Moorella thermoacetica key enzyme in the autotrophic acetyl-CoA pathway, i.e. Wood pathway, enzyme catalyses the final steps in this pathway ?
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Organism

EC Number Organism UniProt Comment Textmining
2.3.1.169 Moorella thermoacetica
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Reaction

EC Number Reaction Comment Organism Reaction ID
2.3.1.169 acetyl-CoA + a [Co(I) corrinoid Fe-S protein] = CO + CoA + a [methyl-Co(III) corrinoid Fe-S protein] pathway Moorella thermoacetica

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.169 CH3-tetrahydrofolate + CO + HS-CoA The methyltransferase catalyses the reaction of CH3-H4folate with the corrinoid/iron-sulfur protein to form a methylcobalt species. The Ni/Fe-S enzyme CO dehydrogease then catalyses the final steps in the formation of acetyl-CoA. Moorella thermoacetica CH3-CO-S-CoA + tetrahydrofolate
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2.3.1.169 CO + methyl-X + HS-CoA
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Moorella thermoacetica CH3-CO-S-CoA + HX
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2.3.1.169 additional information key enzyme in the autotrophic acetyl-CoA pathway, i.e. Wood pathway, enzyme catalyses the final steps in this pathway Moorella thermoacetica ?
-
?