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Literature summary extracted from
- Pyrococcus furiosus glyceraldehyde 3-phosphate oxidoreductase has comparable W6+/5+ and W5+/4+ reduction potentials and unusual [4Fe-4S] EPR properties (1999), FEBS Lett., 462, 66-70.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.2.7.6 | Dithionite | - |
Pyrococcus furiosus |  |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.2.7.6 | Fe2+ | determination of the redox potential | Pyrococcus furiosus | |
| 1.2.7.6 | Fe2+ | 1 [4Fe-4S]2+ cluster per enzyme molecule | Pyrococcus furiosus | |
| 1.2.7.6 | Tungsten | 1 tungsten center per molecule of enzyme | Pyrococcus furiosus | |
| 1.2.7.6 | Tungsten | determination of the redox potential | Pyrococcus furiosus | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.2.7.6 | Pyrococcus furiosus | - |
hyperthermophilic archaeon | - |
| 1.2.7.6 | Pyrococcus furiosus | - |
strain DSM 3638 | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.2.7.6 | - |
Pyrococcus furiosus |
Reaction
| EC Number | Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|---|
| 1.2.7.6 | D-glyceraldehyde-3-phosphate + H2O + oxidized ferredoxin = 3-phospho-D-glycerate + 2 H+ + reduced ferredoxin | electron transfer, mechanism and reduction potential | Pyrococcus furiosus |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 1.2.7.6 | 30 | - |
purified enzyme | Pyrococcus furiosus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.2.7.6 | D-glyceraldehyde-3-phosphate + H2O + oxidized ferredoxin | - |
Pyrococcus furiosus | 3-phospho-D-glycerate + H+ + reduced ferredoxin | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.2.7.6 | glyceraldehyde 3-phosphate oxidoreductase | - |
Pyrococcus furiosus |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.2.7.6 | cubane | - |
Pyrococcus furiosus | |
| 1.2.7.6 | Ferredoxin | - |
Pyrococcus furiosus |
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Release 2023.1 (January 2023)
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