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Literature summary extracted from

  • Liteplo, R.G.; Sribney, M.
    Inhibition of rat liver CDPethanolamine: 1,2-diacylglycerol ethanolamine-phosphotransferase activity by ATP and pantothenic acid derivatives (1977), Can. J. Biochem., 55, 1049-1056.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.8.1 ATP plus pantetheine: inhibition of Mn2+- and Mg2+-activated enzyme, plus CoA: inhibition of Mn2+-activated enzyme, slight stimulation of Mg2+-activated enzyme, ATP alone: inhibition of Mg2+- and Mn2+-activated enzyme Rattus norvegicus
2.7.8.1 Ca2+ Mg2+- or Mn2+-activated enzyme Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.8.1 additional information
-
 additional information
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.8.1 microsome
-
 Rattus norvegicus
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.8.1 Mg2+ Mg2+ at 20 mM or Mn2+ at 1 mM required for optimum activity Rattus norvegicus
2.7.8.1 Mn2+ Mg2+ at 20 mM or Mn2+ at 1 mM required for optimum activity Rattus norvegicus
2.7.8.1 Mn2+ much more effective than Mg2+ Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.7.8.1 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.8.1 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.8.1 CDP-ethanolamine + 1,2-diacylglycerol
-
 Rattus norvegicus CMP + a phosphatidylethanolamine
-
 ?