BRENDA - Enzyme Database

Effect of phospholipase A2 on rat liver microsomal diacylglycerol cholinephosphotransferase, diacylglycerol ethanolaminephosphotransferase and diacylglycerol acyltransferase

Morimoto, K.; Kanoh, H.; Biochim. Biophys. Acta 531, 16-24 (1978)

Data extracted from this reference:

General Stability
EC Number
General Stability
Organism
2.7.8.1
enzyme in rat liver microsomes remains unaffected even if over 90% and almost 100% of microsomal phosphatidylcholine and phosphatidylethanolamine is hydrolyzed by snake venom phospholipase A2
Rattus norvegicus
Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
2.7.8.2
Phospholipase A2
rapid inactivation, microsomal total phospholipids partially reactivate
Rattus norvegicus
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.7.8.1
microsome
-
Rattus norvegicus
-
-
2.7.8.2
microsome
-
Rattus norvegicus
-
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.7.8.1
Rattus norvegicus
-
-
-
2.7.8.2
Rattus norvegicus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.7.8.1
liver
-
Rattus norvegicus
-
2.7.8.2
liver
-
Rattus norvegicus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.8.1
CDP-ethanolamine + 1,2-diacylglycerol
-
644358
Rattus norvegicus
CMP + a phosphatidylethanolamine
-
644358
Rattus norvegicus
-
2.7.8.2
CDP-choline + 1,2-diacylglycerol
-
644358
Rattus norvegicus
CMP + a phosphatidylcholine
-
644358
Rattus norvegicus
-
General Stability (protein specific)
EC Number
General Stability
Organism
2.7.8.1
enzyme in rat liver microsomes remains unaffected even if over 90% and almost 100% of microsomal phosphatidylcholine and phosphatidylethanolamine is hydrolyzed by snake venom phospholipase A2
Rattus norvegicus
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
2.7.8.2
Phospholipase A2
rapid inactivation, microsomal total phospholipids partially reactivate
Rattus norvegicus
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.7.8.1
microsome
-
Rattus norvegicus
-
-
2.7.8.2
microsome
-
Rattus norvegicus
-
-
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.7.8.1
liver
-
Rattus norvegicus
-
2.7.8.2
liver
-
Rattus norvegicus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.8.1
CDP-ethanolamine + 1,2-diacylglycerol
-
644358
Rattus norvegicus
CMP + a phosphatidylethanolamine
-
644358
Rattus norvegicus
-
2.7.8.2
CDP-choline + 1,2-diacylglycerol
-
644358
Rattus norvegicus
CMP + a phosphatidylcholine
-
644358
Rattus norvegicus
-