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Literature summary extracted from

  • Morimoto, K.; Kanoh, H.
    Effect of phospholipase A2 on rat liver microsomal diacylglycerol cholinephosphotransferase, diacylglycerol ethanolaminephosphotransferase and diacylglycerol acyltransferase (1978), Biochim. Biophys. Acta, 531, 16-24.
    View publication on PubMed

General Stability

EC Number General Stability Organism
2.7.8.1 enzyme in rat liver microsomes remains unaffected even if over 90% and almost 100% of microsomal phosphatidylcholine and phosphatidylethanolamine is hydrolyzed by snake venom phospholipase A2 Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.8.2 Phospholipase A2 rapid inactivation, microsomal total phospholipids partially reactivate Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.8.1 microsome
-
 Rattus norvegicus
-
-
2.7.8.2 microsome
-
 Rattus norvegicus
-
-

Organism

EC Number Organism UniProt Comment Textmining
2.7.8.1 Rattus norvegicus
-
-
-
2.7.8.2 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.8.1 liver
-
 Rattus norvegicus
-
2.7.8.2 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.8.1 CDP-ethanolamine + 1,2-diacylglycerol
-
 Rattus norvegicus CMP + a phosphatidylethanolamine
-
 ?
2.7.8.2 CDP-choline + 1,2-diacylglycerol
-
 Rattus norvegicus CMP + a phosphatidylcholine
-
 ?