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Literature summary extracted from

  • Bru, R.; Blöchliger, E.; Luisi, P.L.
    sn-1,2-Diacylglycerol cholinephosphotransferase from pig liver: mixed micellar assay and kinetic analysis of the partially pure enzyme (1993), Arch. Biochem. Biophys., 307, 295-303.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.8.2 dioleoylphosphatidylcholine stimulates Sus scrofa
2.7.8.2 additional information cholinephosphotransferase requires a lipidic boundary for full activation, no activation by substrate Sus scrofa
2.7.8.2 phosphatidylcholine activates Sus scrofa

General Stability

EC Number General Stability Organism
2.7.8.2 soy phosphatidylcholine protects against detergent inactivation Sus scrofa

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.8.2 microsome
-
 Sus scrofa
-
-

Organism

EC Number Organism UniProt Comment Textmining
2.7.8.2 Sus scrofa
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.8.2 partial Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.8.2 liver
-
 Sus scrofa
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.7.8.2 0.0132
-
 30°C, pH 7.4 Sus scrofa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.8.2 CDP-choline + 1,2-diacylglycerol
-
 Sus scrofa CMP + a phosphatidylcholine
-
 ?
2.7.8.2 CDP-choline + didecanoylglycerol at 5-10% of the activity with dioleoylglycerol or egg diglycerides Sus scrofa CMP + didecanoylglycerophosphocholine
-
 ?
2.7.8.2 CDP-choline + dihexanoylglycerol at 5-10% of the activity with dioleoylglycerol or egg diglycerides Sus scrofa CMP + dihexanoylglycerophosphocholine
-
 ?
2.7.8.2 CDP-choline + dioctanoylglycerol at 5-10% of the activity with dioleoylglycerol or egg diglycerides Sus scrofa CMP + dioctanoylglycerophosphocholine
-
 ?
2.7.8.2 additional information utilizes 1-myristyl phosphatidylcholine most rapidly and, in decreasing order the 1-palmitoyl and 1-stearyl species Sus scrofa ?
-
 ?
2.7.8.2 additional information utilizes without marked selectivity the endogenous 1,2-diacylglycerol species differing in the degree of unsaturation Sus scrofa ?
-
 ?