BRENDA - Enzyme Database

Effects of antibiotics, N-acetylaminoacyl-tRNA and other agents on the elongation-factor Tu dependent and ribosome-dependent GTP hydrolysis promoted by 2'(3')-O-L-phenylalanyladenosine

Campuzano, S.; Modolell, J.; Eur. J. Biochem. 117, 27-31 (1981)

Data extracted from this reference:

Activating Compound
EC Number
Activating Compound
Commentary
Organism
Structure
3.6.5.3
bluensomycin
-
Escherichia coli
3.6.5.3
gentamicin C1
-
Escherichia coli
3.6.5.3
gentamicin C1a
-
Escherichia coli
3.6.5.3
hygromycin
-
Escherichia coli
3.6.5.3
kanamycin A
-
Escherichia coli
3.6.5.3
kanamycin B
-
Escherichia coli
3.6.5.3
neomycin C
-
Escherichia coli
3.6.5.3
paromycin
-
Escherichia coli
3.6.5.3
sisomicin
-
Escherichia coli
3.6.5.3
streptomycin
-
Escherichia coli
3.6.5.3
tobramycin
-
Escherichia coli
Application
EC Number
Application
Commentary
Organism
3.6.5.3
medicine
protein biosynthesis
Escherichia coli
Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
3.6.5.3
Chloramphenicol
-
Escherichia coli
3.6.5.3
dihydrostreptomycin
-
Escherichia coli
3.6.5.3
hygromycin A
-
Escherichia coli
3.6.5.3
N-ethylmaleimide
-
Escherichia coli
3.6.5.3
neamine
-
Escherichia coli
3.6.5.3
neomycin B
-
Escherichia coli
3.6.5.3
NH4Cl
at higher concentration
Escherichia coli
3.6.5.3
ribostamycin
-
Escherichia coli
3.6.5.3
sparsomycin
-
Escherichia coli
3.6.5.3
streptogramin A
-
Escherichia coli
3.6.5.3
viomycin
-
Escherichia coli
Metals/Ions
EC Number
Metals/Ions
Commentary
Organism
Structure
3.6.5.3
Mg2+
-
Escherichia coli
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
3.6.5.3
GTP + H2O
Escherichia coli
-
GDP + phosphate
-
Escherichia coli
?
Organism
EC Number
Organism
UniProt
Commentary
Textmining
3.6.5.3
Escherichia coli
-
elongations factor (EF)Tu
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
3.6.5.3
GTP + H2O
-
644144
Escherichia coli
GDP + phosphate
-
644144
Escherichia coli
?
Temperature Optimum [°C]
EC Number
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
3.6.5.3
30
-
-
Escherichia coli
Activating Compound (protein specific)
EC Number
Activating Compound
Commentary
Organism
Structure
3.6.5.3
bluensomycin
-
Escherichia coli
3.6.5.3
gentamicin C1
-
Escherichia coli
3.6.5.3
gentamicin C1a
-
Escherichia coli
3.6.5.3
hygromycin
-
Escherichia coli
3.6.5.3
kanamycin A
-
Escherichia coli
3.6.5.3
kanamycin B
-
Escherichia coli
3.6.5.3
neomycin C
-
Escherichia coli
3.6.5.3
paromycin
-
Escherichia coli
3.6.5.3
sisomicin
-
Escherichia coli
3.6.5.3
streptomycin
-
Escherichia coli
3.6.5.3
tobramycin
-
Escherichia coli
Application (protein specific)
EC Number
Application
Commentary
Organism
3.6.5.3
medicine
protein biosynthesis
Escherichia coli
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
3.6.5.3
Chloramphenicol
-
Escherichia coli
3.6.5.3
dihydrostreptomycin
-
Escherichia coli
3.6.5.3
hygromycin A
-
Escherichia coli
3.6.5.3
N-ethylmaleimide
-
Escherichia coli
3.6.5.3
neamine
-
Escherichia coli
3.6.5.3
neomycin B
-
Escherichia coli
3.6.5.3
NH4Cl
at higher concentration
Escherichia coli
3.6.5.3
ribostamycin
-
Escherichia coli
3.6.5.3
sparsomycin
-
Escherichia coli
3.6.5.3
streptogramin A
-
Escherichia coli
3.6.5.3
viomycin
-
Escherichia coli
Metals/Ions (protein specific)
EC Number
Metals/Ions
Commentary
Organism
Structure
3.6.5.3
Mg2+
-
Escherichia coli
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
3.6.5.3
GTP + H2O
Escherichia coli
-
GDP + phosphate
-
Escherichia coli
?
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
3.6.5.3
GTP + H2O
-
644144
Escherichia coli
GDP + phosphate
-
644144
Escherichia coli
?
Temperature Optimum [°C] (protein specific)
EC Number
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
3.6.5.3
30
-
-
Escherichia coli