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Literature summary extracted from

  • Tieku, S.; Hooper, N.M.
    Inhibitor profile of porcine aminopeptidase W (1993), Biochem. Soc. Trans., 21, 250S.
No PubMed abstract available

Application

EC Number Application Comment Organism
3.4.11.16 medicine chemotherapeutic target, involved in heart disease, metastasis, inflammation Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.11.16 amastatin 50% inhibition at 0.00158 mM Sus scrofa
3.4.11.16 bestatin
-
 Homo sapiens
3.4.11.16 bestatin 50% inhibition at 0.0079 mM Sus scrofa
3.4.11.16 additional information overlap of inhibitory effects of typical aminopeptidase inhibitors with other enzymes Sus scrofa
3.4.11.16 probestin 50% inhibition at 0.005 mM Sus scrofa
3.4.11.16 rentiapril 50% inhibition at 0.0016 mM Sus scrofa
3.4.11.16 zofenoprilat 50% inhibition at 0.018 mM Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
3.4.11.16 Homo sapiens
-
-
-
3.4.11.16 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.11.16 peripheral nervous system
-
 Homo sapiens
-

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.4.11.16 37
-
 assay at Homo sapiens
3.4.11.16 37
-
 assay at Sus scrofa

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.11.16 7.4
-
 assay at Sus scrofa