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Literature summary extracted from

  • Tieku, S.; Hooper, M.
    Inhibition of aminopeptidases N, A, and W (1992), Biochem. Pharmacol., 44, 1725-1730.
    View publication on PubMed

Application

EC Number Application Comment Organism
3.4.11.16 medicine chemotherapeutic target, involved in heart disease, metastasis, inflammation Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.11.16 amastatin 100% inhibition at 0.1 mM Sus scrofa
3.4.11.16 arphamenine A 50% inhibition at 0.1 mM Sus scrofa
3.4.11.16 Arphamenine B 7% inhibition at 0.1 mM Sus scrofa
3.4.11.16 bestatin some of the observed chemotherapeutic actions of bestatin may be due to inhibition of enzyme Homo sapiens
3.4.11.16 bestatin 89% inhibition at 0.1 mM Sus scrofa
3.4.11.16 captopril 56% inhibition at 0.1 mM Sus scrofa
3.4.11.16 cilazaprilat 27% inhibition at 0.1 mM Sus scrofa
3.4.11.16 lisinopril 28% inhibition at 0.1 mM Sus scrofa
3.4.11.16 pentoprilat 27% inhibition at 0.1 mM Sus scrofa
3.4.11.16 probestin % inhibition at 0.1 mM Sus scrofa
3.4.11.16 rentiapril 100% inhibition at 0.1 mM Sus scrofa
3.4.11.16 spiraprilat 28% inhibition at 0.1 mM Sus scrofa
3.4.11.16 zofenoprilat 82% inhibition at 0.1 mM Sus scrofa

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Organism

EC Number Organism UniProt Comment Textmining
3.4.11.16 Homo sapiens
-
-
-
3.4.11.16 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.11.16 kidney
-
 Sus scrofa
-