EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
3.1.3.52 | histone H3 | stimulates at 0.036 mg/ml | Bos taurus | |
3.1.3.52 | poly(L-arginine) | stimulates 1.5-3fold at 0.0036 mg/ml | Bos taurus | |
3.1.3.52 | poly(L-lysine) | stimulates 1.5-3fold at 0.0036 mg/ml | Bos taurus | |
3.1.3.52 | protamine | stimulates 1.5-3fold at 0.0036 mg/ml | Bos taurus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.1.3.52 | acyl-CoA | - |
Bos taurus | |
3.1.3.52 | ADP | 50% inhibition at 400 mM; inhibition is completely reversed by Mg2+ | Bos taurus | |
3.1.3.52 | ATP | 50% inhibition at 200 mM; inhibition is completely reversed by Mg2+ | Bos taurus | |
3.1.3.52 | CDP | 50% inhibition at 400 mM; inhibition is completely reversed by Mg2+ | Bos taurus | |
3.1.3.52 | CoA | - |
Bos taurus | |
3.1.3.52 | CTP | 50% inhibition at 250 mM; inhibition is completely reversed by Mg2+ | Bos taurus | |
3.1.3.52 | GDP | 50% inhibition at 200 mM; inhibition is completely reversed by Mg2+ | Bos taurus | |
3.1.3.52 | GTP | 50% inhibition at 60 mM; inhibition is completely reversed by Mg2+ | Bos taurus | |
3.1.3.52 | guanosine 5'-(beta,gamma-imido)triphosphate | - |
Bos taurus | |
3.1.3.52 | heparin | - |
Bos taurus | |
3.1.3.52 | Inhibitor protein | purification of heat- and acid-stable inhibitor protein, which regulates activity | Bos taurus | |
3.1.3.52 | additional information | little inhibitory effect: AMP; little inhibitory effect: GMP; little inhibitory effect: NAD+; little inhibitory effect: NADH; little inhibitory effect: UMP | Bos taurus | |
3.1.3.52 | nucleoside diphosphates | inhibition is completely reversed by Mg2+ | Bos taurus | |
3.1.3.52 | nucleoside triphosphates | inhibition is completely reversed by Mg2+ | Bos taurus | |
3.1.3.52 | UDP | 50% inhibition at 250 mM; inhibition is completely reversed by Mg2+ | Bos taurus | |
3.1.3.52 | UTP | 50% inhibition at 100 mM; inhibition is completely reversed by Mg2+ | Bos taurus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
3.1.3.52 | mitochondrion | inner membrane-matrix compartment | Bos taurus | 5739 | - |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
3.1.3.52 | additional information | active in absence of divalent cation | Bos taurus |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
3.1.3.52 | 460000 | - |
gel filtration | Bos taurus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.3.52 | [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)] phosphate + H2O | Bos taurus | - |
[3-methyl-2-oxobutanoate dehydrogenase (lipoamide)] + phosphate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.3.52 | Bos taurus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.1.3.52 | - |
Bos taurus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.1.3.52 | kidney | - |
Bos taurus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
3.1.3.52 | 0.158 | - |
- |
Bos taurus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.3.52 | [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)] phosphate + H2O | - |
Bos taurus | [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)] + phosphate | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
3.1.3.52 | More | enzyme is associated with the 3-methyl-2-oxobutanoate dehydrogenase complex | Bos taurus |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.1.3.52 | 0.00000013 | - |
Inhibitor protein | pH 7.3, 30°C | Bos taurus |