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Literature summary extracted from

  • Steinberg, T.H.; Mathews, D.E.; Durbin, R.D.; Burgess, R.R.
    Tagetitoxin: a new inhibitor of eukaryotic transcription by RNA polymerase III (1990), J. Biol. Chem., 265, 499-505.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.7.6 Tagetitoxin inhibition of RNA polymerase III Bombyx mori
2.7.7.6 Tagetitoxin no inhibition of calf thymus RNA polymerase II Bos taurus
2.7.7.6 Tagetitoxin inhibition of RNA polymerase III Homo sapiens
2.7.7.6 Tagetitoxin inhibition of RNA polymerase III Saccharomyces cerevisiae
2.7.7.6 Tagetitoxin inhibition of RNA polymerase III Xenopus laevis

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.6 Bombyx mori
-
-
-
2.7.7.6 Bos taurus
-
-
-
2.7.7.6 Homo sapiens
-
-
-
2.7.7.6 Saccharomyces cerevisiae
-
-
-
2.7.7.6 Xenopus laevis
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.7.6 HeLa cell
-
Homo sapiens
-
2.7.7.6 oocyte
-
Xenopus laevis
-
2.7.7.6 thymus
-
Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.6 nucleoside triphosphate + RNAn the enzyme requires DNA as template Homo sapiens diphosphate + RNAn+1
-
?
2.7.7.6 nucleoside triphosphate + RNAn the enzyme requires DNA as template Saccharomyces cerevisiae diphosphate + RNAn+1
-
?
2.7.7.6 nucleoside triphosphate + RNAn the enzyme requires DNA as template Bos taurus diphosphate + RNAn+1
-
?
2.7.7.6 nucleoside triphosphate + RNAn the enzyme requires DNA as template Bombyx mori diphosphate + RNAn+1
-
?
2.7.7.6 nucleoside triphosphate + RNAn the enzyme requires DNA as template Xenopus laevis diphosphate + RNAn+1
-
?