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Literature summary extracted from

  • Booth, J.W.; Guidotti, G.
    An alleged yeast polyphosphate kinase is actually diadenosine-5', 5"'-P1,P4-tetraphosphate alpha,beta-phosphorylase (1995), J. Biol. Chem., 270, 19377-19382.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.7.53 AMP ADP/phosphate-exchange Saccharomyces cerevisiae
2.7.7.53 Mg2+ inhibitory in presence of phosphate for ADP/phosphate exchange reaction Saccharomyces cerevisiae
2.7.7.53 P1,P4-bis(5'-adenosyl) tetraphosphate ADP/phosphate-exchange Saccharomyces cerevisiae

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.7.53 Mg2+ inhibitory in presence of phosphate for ADP/phosphate exchange reaction Saccharomyces cerevisiae

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.7.53 40000
-
 1 * 40000, SDS-PAGE Saccharomyces cerevisiae

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.53 Saccharomyces cerevisiae
-
 2 isoforms APA1 and APA2
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.53 ADP + phosphate 90% activity due to isoform I Saccharomyces cerevisiae phosphate + ADP
-
 r
2.7.7.53 ADP + phosphate ADP/phosphate exchange reaction Saccharomyces cerevisiae phosphate + ADP
-
 r
2.7.7.53 NDP + phosphate enzyme performs the exchange reaction also with polyphosphates Saccharomyces cerevisiae phosphate + NDP
-
 r
2.7.7.53 NDP + phosphate 90% activity due to isoform I Saccharomyces cerevisiae phosphate + NDP
-
 r
2.7.7.53 NDP + polyphosphate exchange reaction Saccharomyces cerevisiae polyphosphate + NDP
-
 r
2.7.7.53 P1,P4-bis(5'-adenosyl) tetraphosphate + arsenate irreversible formation of reaction intermediate AMP-enzyme, unstable Saccharomyces cerevisiae ?
-
 ir
2.7.7.53 P1,P4-bis(5'-adenosyl) tetraphosphate + phosphate AMP-enzyme intermediate Saccharomyces cerevisiae ADP + ATP
-
 r

Subunits

EC Number Subunits Comment Organism
2.7.7.53 monomer 1 * 40000, SDS-PAGE Saccharomyces cerevisiae

Synonyms

EC Number Synonyms Comment Organism
2.7.7.53 Ap4A phosphorylase
-
 Saccharomyces cerevisiae
2.7.7.53 diadenosine 5',5'''-P1,P4-tetraphosphate alpha,beta-phosphorylase
-
 Saccharomyces cerevisiae