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Literature summary extracted from

  • Behrens, S.E.; Tomei, L.; De Francesco, R.
    Identification and properties of the RNA-dependent RNA polymerase of Hepatitis C virus (1996), EMBO J., 15, 12-22.
    View publication on PubMedView publication on EuropePMC

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.7.48 65000
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 Hepacivirus C

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.7.48 nucleoside triphosphate + RNAn Hepacivirus C replication of Hepatitits C virus is thought to proceed via the initial synthesis of a complementary (-)RNA strand, which serves, in turn, as a template for the production of progeny (+)-strand RNA molecules. An RNA-dependent RNA polymerase is postulated to be involved in these steps diphosphate + RNAn+1
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 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.48 Hepacivirus C
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.48 nucleoside triphosphate + RNAn the enzyme performs RNA- or DNA oligonucleotide primer-dependent RNA synthesis on templates with a blocked 3' end or on homopolymeric templates Hepacivirus C diphosphate + RNAn+1
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 ?
2.7.7.48 nucleoside triphosphate + RNAn replication of Hepatitits C virus is thought to proceed via the initial synthesis of a complementary (-)RNA strand, which serves, in turn, as a template for the production of progeny (+)-strand RNA molecules. An RNA-dependent RNA polymerase is postulated to be involved in these steps Hepacivirus C diphosphate + RNAn+1
-
 ?