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Literature summary extracted from

  • Morrow, C.D.; Lubrinski, J.; Hocko, J.; Gibbons, G.F.; Dasgupta, A.
    Purification of a soluble template-dependent Rhinovirus RNA polymerase and its dependence on a host cell protein for viral RNA synthesis (1985), J. Virol., 53, 266-272.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.7.48 KCl 50 mM, 90% inhibition rhinovirus A2

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.7.48 additional information enzyme is localized in the soluble phase of infected Hela cells rhinovirus A2
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.7.48 Zn2+ 0.05 mM, maximal stimulation of fourfold compared with the control rhinovirus A2

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.7.48 64000
-
 x * 64000, SDS-PAGE rhinovirus A2

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.48 rhinovirus A2
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.7.48
-
 rhinovirus A2

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.7.7.48 0.00196
-
-
 rhinovirus A2

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.48 nucleoside triphosphate + RNAn
-
 rhinovirus A2 diphosphate + RNAn+1
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.7.48 ? x * 64000, SDS-PAGE rhinovirus A2

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.7.48 7.6
-
-
 rhinovirus A2

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.7.7.48 7.2 8 pH 7.2: about 60% of maximal activity, pH 8.0: about 60% of maximal activity rhinovirus A2