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Literature summary extracted from

  • Tauch, A.; Goetker, S.; Puehler, A.; Kalinowski, J.; Thierbach, G.
    The 27.8-kb R-plasmid pTET3 from Corynebacterium glutamicum encodes the aminoglycoside adenyltransferase gene cassette aadA9 and the regulated tetracycline efflux system Tet 33 flanked by active copies of the widespread insertion sequence IS6100 (2002), Plasmid, 48, 117-129.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.7.47 27.8 kb R-plasmid pTET3 gene cassette aadA9, antibiotic resistance region identified in Mycobacterium fortuitum, cloned in Escherichia coli DH5alphaMCR Corynebacterium glutamicum

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.7.47 31000
-
 deduced from open reading frame Corynebacterium glutamicum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.7.47 ATP + streptomycin Corynebacterium glutamicum
-
 diphosphate + 3''-adenylylstreptomycin
-
 ?
2.7.7.47 ATP + streptomycin Corynebacterium glutamicum LP-6
-
 diphosphate + 3''-adenylylstreptomycin
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.47 Corynebacterium glutamicum
-
 LP-6
-
2.7.7.47 Corynebacterium glutamicum LP-6
-
 LP-6
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.47 ATP + spectinomycin inactivation of the antibiotic by adenylating the 9-hydroxyl-group Corynebacterium glutamicum diphosphate + 9-adenylylspectinomycin
-
 ?
2.7.7.47 ATP + spectinomycin inactivation of the antibiotic by adenylating the 9-hydroxyl-group Corynebacterium glutamicum LP-6 diphosphate + 9-adenylylspectinomycin
-
 ?
2.7.7.47 ATP + streptomycin
-
 Corynebacterium glutamicum diphosphate + 3''-adenylylstreptomycin
-
 ?
2.7.7.47 ATP + streptomycin
-
 Corynebacterium glutamicum LP-6 diphosphate + 3''-adenylylstreptomycin
-
 ?
2.7.7.47 ATP + tetracyclin
-
 Corynebacterium glutamicum diphosphate + 3''adenylyltetracyclin
-
 ?
2.7.7.47 ATP + tetracyclin
-
 Corynebacterium glutamicum LP-6 diphosphate + 3''adenylyltetracyclin
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.7.47 aminoglycoside adenyltransferase
-
 Corynebacterium glutamicum