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Literature summary extracted from

  • Worrall, D.M.; Lambert, S.F.; Tubbs, P.K.
    Limited proteolysis of pig liver CoA synthase: evidence for subunit identity (1985), FEBS Lett., 187, 277-279.
    View publication on PubMed

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.1.24 61000
-
2 * 61000, SDS-PAGE, subunit structure Sus scrofa
2.7.1.24 118000
-
gel filtration Sus scrofa
2.7.7.3 61000
-
alpha2, 2 * 61000, SDS-PAGE, subunit structure Sus scrofa
2.7.7.3 118000
-
gel filtration Sus scrofa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.7.3 ATP + pantetheine 4'-phosphate Rattus norvegicus
-
diphosphate + 3'-dephospho-CoA
-
?
2.7.7.3 ATP + pantetheine 4'-phosphate Sus scrofa
-
diphosphate + 3'-dephospho-CoA
-
?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.24 Sus scrofa
-
-
-
2.7.7.3 Rattus norvegicus
-
-
-
2.7.7.3 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.24 liver
-
Sus scrofa
-
2.7.7.3 liver
-
Rattus norvegicus
-
2.7.7.3 liver
-
Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.24 ATP + dephospho-CoA
-
Sus scrofa ADP + CoA
-
?
2.7.7.3 ATP + pantetheine 4'-phosphate
-
Rattus norvegicus diphosphate + 3'-dephospho-CoA
-
?
2.7.7.3 ATP + pantetheine 4'-phosphate
-
Sus scrofa diphosphate + 3'-dephospho-CoA
-
?

Subunits

EC Number Subunits Comment Organism
2.7.1.24 dimer 2 * 61000, SDS-PAGE, subunit structure Sus scrofa
2.7.7.3 dimer alpha2, 2 * 61000, SDS-PAGE, subunit structure Sus scrofa

Synonyms

EC Number Synonyms Comment Organism
2.7.1.24 More bifunctional enzyme with phosphopantetheine adenylyltransferase activity, EC 2.7.7.3, and dephospho-CoA kinase activity, EC 2.7.1.24 Sus scrofa
2.7.1.24 More bifunctional enzyme is termed CoA-synthetase Sus scrofa
2.7.7.3 More with EC 2.7.1.24 part of a bifunctional enzyme with EC 2.7.1.24 Rattus norvegicus
2.7.7.3 More with EC 2.7.1.24 part of a bifunctional enzyme with EC 2.7.1.24 Sus scrofa