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Literature summary extracted from

  • Novelli, G.D.
    Enzymatic synthesis and structure of CoA (1953), Fed. Proc., 12, 675-681.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.1.34 cytosol
-
 Sus scrofa 5829
-
2.7.1.34 cytosol
-
 Columba sp. 5829
-
2.7.1.34 additional information not in microsomes or mitochondria Sus scrofa
-
-
2.7.1.34 additional information not in microsomes or mitochondria Columba sp.
-
-
2.7.7.3 cytosol
-
 Sus scrofa 5829
-
2.7.7.3 cytosol
-
 Columba sp. 5829
-
2.7.7.3 mitochondrion
-
 Sus scrofa 5739
-
2.7.7.3 mitochondrion
-
 Columba sp. 5739
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.1.24 Mg2+ requirement Rattus norvegicus
2.7.1.24 Mg2+ requirement Sus scrofa
2.7.1.24 Mg2+ requirement Columba sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.24 ATP + dephospho-CoA Rattus norvegicus
-
 ADP + CoA
-
 ?
2.7.1.24 ATP + dephospho-CoA Sus scrofa
-
 ADP + CoA
-
 ?
2.7.1.24 ATP + dephospho-CoA Columba sp.
-
 ADP + CoA
-
 ?
2.7.1.34 ATP + pantetheine Sus scrofa involved in biosynthesis of CoA ADP + pantetheine 4'-phosphate
-
 ?
2.7.1.34 ATP + pantetheine Columba sp. involved in biosynthesis of CoA ADP + pantetheine 4'-phosphate
-
 ?
2.7.7.3 ATP + pantetheine 4'-phosphate Sus scrofa involved in coenzyme A biosynthesis diphosphate + 3'-dephospho-CoA
-
 r
2.7.7.3 ATP + pantetheine 4'-phosphate Columba sp. involved in coenzyme A biosynthesis diphosphate + 3'-dephospho-CoA
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.24 Columba sp.
-
-
-
2.7.1.24 Rattus norvegicus
-
-
-
2.7.1.24 Sus scrofa
-
-
-
2.7.1.34 Columba sp.
-
-
-
2.7.1.34 Sus scrofa
-
-
-
2.7.7.3 Columba sp.
-
-
-
2.7.7.3 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.34 liver
-
 Sus scrofa
-
2.7.1.34 liver
-
 Columba sp.
-
2.7.7.3 liver
-
 Sus scrofa
-
2.7.7.3 liver
-
 Columba sp.
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.7.1.34 additional information
-
-
 Columba sp.

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.24 ATP + dephospho-CoA
-
 Rattus norvegicus ADP + CoA
-
 ?
2.7.1.24 ATP + dephospho-CoA
-
 Sus scrofa ADP + CoA
-
 ?
2.7.1.24 ATP + dephospho-CoA
-
 Columba sp. ADP + CoA
-
 ?
2.7.1.34 ATP + pantetheine
-
 Sus scrofa ADP + pantetheine 4'-phosphate
-
 ?
2.7.1.34 ATP + pantetheine
-
 Columba sp. ADP + pantetheine 4'-phosphate
-
 ?
2.7.1.34 ATP + pantetheine involved in biosynthesis of CoA Sus scrofa ADP + pantetheine 4'-phosphate
-
 ?
2.7.1.34 ATP + pantetheine involved in biosynthesis of CoA Columba sp. ADP + pantetheine 4'-phosphate
-
 ?
2.7.7.3 ATP + pantetheine 4'-phosphate
-
 Sus scrofa diphosphate + 3'-dephospho-CoA
-
 r
2.7.7.3 ATP + pantetheine 4'-phosphate
-
 Columba sp. diphosphate + 3'-dephospho-CoA
-
 r
2.7.7.3 ATP + pantetheine 4'-phosphate involved in coenzyme A biosynthesis Sus scrofa diphosphate + 3'-dephospho-CoA
-
 r
2.7.7.3 ATP + pantetheine 4'-phosphate involved in coenzyme A biosynthesis Columba sp. diphosphate + 3'-dephospho-CoA
-
 r