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Literature summary extracted from

  • Ferro, A.M.; Kuehl, L.
    Adenosine triphosphate: nicotinamide mononucleotide adenylyltransferase of pig liver. Purification and properties (1975), Biochim. Biophys. Acta, 410, 285-298.
    View publication on PubMed

General Stability

EC Number General Stability Organism
2.7.7.1 dithiothreitol stabilizes during purification Sus scrofa

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.7.1 NaCl reverse reaction Sus scrofa

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.7.1 0.088
-
 ATP pH 8 Sus scrofa
2.7.7.1 0.11
-
 ATP
-
 Sus scrofa
2.7.7.1 0.12
-
 nicotinamide ribonucleotide
-
 Sus scrofa

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.7.1 Mg2+ requirement Sus scrofa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.7.1 ATP + nicotinamide ribonucleotide Rattus norvegicus
-
 diphosphate + NAD+
-
 r
2.7.7.1 ATP + nicotinamide ribonucleotide Sus scrofa
-
 diphosphate + NAD+
-
 r
2.7.7.1 ATP + nicotinamide ribonucleotide Bos taurus
-
 diphosphate + NAD+
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.1 Bos taurus
-
-
-
2.7.7.1 Rattus norvegicus
-
-
-
2.7.7.1 Sus scrofa
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.7.1 partial Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.7.1 liver
-
 Rattus norvegicus
-
2.7.7.1 liver
-
 Sus scrofa
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.7.7.1 40
-
-
 Sus scrofa

Storage Stability

EC Number Storage Stability Organism
2.7.7.1 -27°C, several months Sus scrofa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.1 ATP + nicotinamide ribonucleotide
-
 Rattus norvegicus diphosphate + NAD+
-
 r
2.7.7.1 ATP + nicotinamide ribonucleotide
-
 Sus scrofa diphosphate + NAD+
-
 r
2.7.7.1 ATP + nicotinamide ribonucleotide
-
 Bos taurus diphosphate + NAD+
-
 r
2.7.7.1 ATP + nicotinamide ribonucleotide i.e. NMN or nicotinamide mononucleotide Rattus norvegicus diphosphate + NAD+
-
 r
2.7.7.1 ATP + nicotinamide ribonucleotide i.e. NMN or nicotinamide mononucleotide Sus scrofa diphosphate + NAD+
-
 r
2.7.7.1 ATP + nicotinamide ribonucleotide i.e. NMN or nicotinamide mononucleotide Bos taurus diphosphate + NAD+
-
 r

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
2.7.7.1 4
-
 10 min stable at pH 3.5-9.5 Sus scrofa

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
2.7.7.1 3.5 9.5 10 min stable at 4°C Sus scrofa

pI Value

EC Number Organism Comment pI Value Maximum pI Value
2.7.7.1 Sus scrofa pH-electrophoretic mobility curve
-
 5