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Literature summary extracted from

  • Kimura, N.; Shimada, N.
    Membrane-associated nucleoside diphosphate kinase from rat liver. Purification, characterization, and comparison with cytosolic enzyme (1988), J. Biol. Chem., 263, 4647-4653.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.4.6 0.031
-
 GDP cosubstrate ATP, cytosolic kinase Rattus norvegicus
2.7.4.6 0.036
-
 GDP cosubstrate ATP, membrane-associated kinase Rattus norvegicus
2.7.4.6 0.042
-
 ADP cosubstrate ATP, cytosolic kinase Rattus norvegicus
2.7.4.6 0.073
-
 ADP cosubstrate ATP, membrane-associated kinase Rattus norvegicus
2.7.4.6 0.16
-
 UDP cosubstrate ATP, membrane-associated kinase Rattus norvegicus
2.7.4.6 0.19
-
 UDP cosubstrate ATP, cytosolic kinase Rattus norvegicus
2.7.4.6 0.5 0.54 CDP cosubstrate ATP Rattus norvegicus
2.7.4.6 0.5 0.54 CDP cytosolic kinase Rattus norvegicus
2.7.4.6 0.69
-
 CDP cosubstrate ATP, membrane-associated kinase Rattus norvegicus
2.7.4.6 1.33
-
 ATP cosubstrate GDP, cytosolic kinase Rattus norvegicus
2.7.4.6 1.66
-
 ATP cosubstrate GDP, membrane-associated kinase Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.4.6 cytoplasmic membrane cytosolic and plasma membrane-associated enzymes are quite similar, if not identical Rattus norvegicus
-
-
2.7.4.6 cytosol cytosolic and plasma membrane-associated enzymes are quite similar, if not identical Rattus norvegicus 5829
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.4.6 99700
-
 sucrose density gradient centrifugation Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.4.6 NDP + NTP Rattus norvegicus major component of nucleoside triphosphate synthetic pathway NTP + NDP
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.4.6 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.4.6
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.4.6 liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.7.4.6 additional information
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.4.6 ATP + ADP
-
 Rattus norvegicus ADP + ATP
-
 ?
2.7.4.6 ATP + CDP
-
 Rattus norvegicus ADP + CTP
-
 ?
2.7.4.6 ATP + UDP
-
 Rattus norvegicus ADP + UTP
-
 ?
2.7.4.6 GTP + ADP
-
 Rattus norvegicus GDP + ATP
-
 r
2.7.4.6 NDP + NTP major component of nucleoside triphosphate synthetic pathway Rattus norvegicus NTP + NDP
-
 ?
2.7.4.6 NTP + nucleoside diphosphate
-
 Rattus norvegicus NDP + NTP
-
 ?