EC Number | General Stability | Organism |
---|---|---|
2.7.2.1 | stabilized during storage by L-cysteine | Escherichia coli |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.7.2.1 | HgCl2 | - |
Escherichia coli | |
2.7.2.1 | Iodosobenzoate | - |
Escherichia coli | |
2.7.2.1 | p-mercuribenzoate | - |
Escherichia coli |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.7.2.1 | 1.5 | - |
ADP | pH 7.4 | Escherichia coli | |
2.7.2.1 | 5 | - |
acetyl phosphate | pH 7.4 | Escherichia coli | |
2.7.2.1 | 90 | - |
acetate | pH 7.4 | Streptococcus pyogenes | |
2.7.2.1 | 300 | - |
acetate | pH 7.4 | Escherichia coli |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.7.2.1 | Mg2+ | absolute requirement at pH 7.4 | Escherichia coli |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.2.1 | ATP + acetate | Streptococcus pyogenes | - |
ADP + acetyl phosphate | - |
r | |
2.7.2.1 | ATP + acetate | Lactobacillus delbrueckii | - |
ADP + acetyl phosphate | - |
r | |
2.7.2.1 | ATP + acetate | Escherichia coli | acetate kinase/phosphotransacetylase, major role of this two-enzyme sequence is to provide acetyl coenzyme A which may participate in fatty acid synthesis, citrate formation and subsequent oxidation | ADP + acetyl phosphate | - |
r |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.2.1 | Escherichia coli | - |
- |
- |
2.7.2.1 | Lactobacillus delbrueckii | - |
- |
- |
2.7.2.1 | Streptococcus pyogenes | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.7.2.1 | - |
Escherichia coli |
2.7.2.1 | - |
Streptococcus pyogenes |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.7.2.1 | 282 | - |
- |
Streptococcus pyogenes |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.2.1 | ATP + acetate | - |
Escherichia coli | ADP + acetyl phosphate | - |
r | |
2.7.2.1 | ATP + acetate | - |
Streptococcus pyogenes | ADP + acetyl phosphate | - |
r | |
2.7.2.1 | ATP + acetate | - |
Lactobacillus delbrueckii | ADP + acetyl phosphate | - |
r | |
2.7.2.1 | ATP + acetate | acetate kinase/phosphotransacetylase, major role of this two-enzyme sequence is to provide acetyl coenzyme A which may participate in fatty acid synthesis, citrate formation and subsequent oxidation | Escherichia coli | ADP + acetyl phosphate | - |
r | |
2.7.2.1 | ATP + propionate | one-tenth of the rate shown with acetate | Escherichia coli | ADP + propionyl phosphate | - |
r | |
2.7.2.1 | ITP + acetate | - |
Escherichia coli | IDP + acetyl phosphate | - |
r | |
2.7.2.1 | additional information | formate, butyrate and various holo and hydroxy derivatives of acetate and propionate are not phosphorylated | Escherichia coli | ? | - |
? |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.7.2.1 | 7.5 | - |
- |
Escherichia coli |
EC Number | pH Stability | pH Stability Maximum | Comment | Organism |
---|---|---|---|---|
2.7.2.1 | 6.5 | 7.8 | enzyme undergoes irreversible inactivation outside this range | Escherichia coli |