BRENDA - Enzyme Database

Deoxycytidine kinase. 3. Kinetics and allosteric regulation of the calf thymus enzyme

Ives, D.H.; Durham, J.P.; J. Biol. Chem. 245, 2285-2294 (1970)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
2.7.1.74
dCTP
kinetics; reversible by dTTP; reversible by UDP
Bos taurus
2.7.1.74
dTTP
at increased deoxycytidine concentrations
Bos taurus
2.7.1.74
UDP
-
Bos taurus
Metals/Ions
EC Number
Metals/Ions
Commentary
Organism
Structure
2.7.1.74
Mg2+
Mg2+/ATP complex is the reactive species
Bos taurus
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.7.1.74
Bos taurus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.7.1.74
thymus
-
Bos taurus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.1.74
ATP + 2'-deoxycytidine
-
641932
Bos taurus
ADP + 5'-dCMP
-
641932
Bos taurus
?
2.7.1.74
dTTP + 2'-deoxycytidine
-
641932
Bos taurus
dTDP + 2'-deoxy-CMP
-
-
-
?
2.7.1.74
NTP + deoxycytidine
-
641932
Bos taurus
NDP + dCMP
-
641932
Bos taurus
?
2.7.1.74
NTP + deoxyguanosine
-
641932
Bos taurus
NDP + dGMP
-
-
-
?
Temperature Optimum [C]
EC Number
Temperature Optimum [C]
Temperature Optimum Maximum [C]
Commentary
Organism
2.7.1.74
37
-
assay at
Bos taurus
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
2.7.1.74
dCTP
kinetics; reversible by dTTP; reversible by UDP
Bos taurus
2.7.1.74
dTTP
at increased deoxycytidine concentrations
Bos taurus
2.7.1.74
UDP
-
Bos taurus
Metals/Ions (protein specific)
EC Number
Metals/Ions
Commentary
Organism
Structure
2.7.1.74
Mg2+
Mg2+/ATP complex is the reactive species
Bos taurus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.7.1.74
thymus
-
Bos taurus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.1.74
ATP + 2'-deoxycytidine
-
641932
Bos taurus
ADP + 5'-dCMP
-
641932
Bos taurus
?
2.7.1.74
dTTP + 2'-deoxycytidine
-
641932
Bos taurus
dTDP + 2'-deoxy-CMP
-
-
-
?
2.7.1.74
NTP + deoxycytidine
-
641932
Bos taurus
NDP + dCMP
-
641932
Bos taurus
?
2.7.1.74
NTP + deoxyguanosine
-
641932
Bos taurus
NDP + dGMP
-
-
-
?
Temperature Optimum [C] (protein specific)
EC Number
Temperature Optimum [C]
Temperature Optimum Maximum [C]
Commentary
Organism
2.7.1.74
37
-
assay at
Bos taurus