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Literature summary extracted from

  • Ives, D.H.; Durham, J.P.
    Deoxycytidine kinase. 3. Kinetics and allosteric regulation of the calf thymus enzyme (1970), J. Biol. Chem., 245, 2285-2294.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.74 dCTP kinetics; reversible by dTTP; reversible by UDP Bos taurus
2.7.1.74 dTTP at increased deoxycytidine concentrations Bos taurus
2.7.1.74 UDP
-
 Bos taurus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.1.74 Mg2+ Mg2+/ATP complex is the reactive species Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.74 Bos taurus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.74 thymus
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.74 ATP + 2'-deoxycytidine
-
 Bos taurus ADP + 5'-dCMP
-
 ?
2.7.1.74 dTTP + 2'-deoxycytidine
-
 Bos taurus dTDP + 2'-deoxy-CMP
-
 ?
2.7.1.74 NTP + deoxycytidine
-
 Bos taurus NDP + dCMP
-
 ?
2.7.1.74 NTP + deoxyguanosine
-
 Bos taurus NDP + dGMP
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.7.1.74 37
-
 assay at Bos taurus