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Literature summary extracted from

  • Kalin, J.R.; Allen, C.M.
    Characterization of undecaprenol kinase from Lactobacillus plantarum (1979), Biochim. Biophys. Acta, 574, 112-122.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.1.66 DMSO required Lactiplantibacillus plantarum
2.7.1.66 Triton X-100 required Lactiplantibacillus plantarum

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.66 K2HPO4 above 10 mM Lactiplantibacillus plantarum
2.7.1.66 KCl above 10 mM Lactiplantibacillus plantarum
2.7.1.66 Mg2+ above 10 mM Lactiplantibacillus plantarum
2.7.1.66 Na2HPO4 above 10 mM Lactiplantibacillus plantarum
2.7.1.66 NaCl above 10 mM Lactiplantibacillus plantarum
2.7.1.66 NaF above 5 mM Lactiplantibacillus plantarum
2.7.1.66 NH4Cl above 10 mM Lactiplantibacillus plantarum

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.1.66 0.014
-
 dolichol pH 8.0, 33°C Lactiplantibacillus plantarum
2.7.1.66 0.014
-
 undecaprenol pH 8.0, 33°C Lactiplantibacillus plantarum
2.7.1.66 2
-
 ATP pH 8.0, 33°C, reaction with undecaprenol Lactiplantibacillus plantarum

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.1.66 membrane bound to Lactiplantibacillus plantarum 16020
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.1.66 Co2+ can partially replace Mg2+ in activation, 25% of the activation with Mg2+, optimal concentration is 10 mM Lactiplantibacillus plantarum
2.7.1.66 Mg2+ required, optimal activation at 10 mM Lactiplantibacillus plantarum
2.7.1.66 Mg2+ optimum concentration: 0.01 M Lactiplantibacillus plantarum
2.7.1.66 Mn2+ can partially replace Mg2+ in activation Lactiplantibacillus plantarum
2.7.1.66 Mn2+ 50% of the activation with Mg2+, optimal concentration is 2.5 mM Lactiplantibacillus plantarum
2.7.1.66 NaF 1.25 mM stimulates Lactiplantibacillus plantarum

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.66 Lactiplantibacillus plantarum
-
 ATCC 8014
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.66 ATP + (E,E,E)-geranylgeraniol 5%, of the activity with ATP Lactiplantibacillus plantarum ADP + (E,E,E)-geranylgeraniyl phosphate
-
 ?
2.7.1.66 ATP + (Z,E,E)-geranylgeraniol 5% of the activity with undecaprenol Lactiplantibacillus plantarum ADP + (Z,E,E)-geranylgeraniyl phosphate
-
 ?
2.7.1.66 ATP + dolichol 13% of the activity with undecaprenol Lactiplantibacillus plantarum ADP + dolichyl phosphate
-
 ?
2.7.1.66 ATP + solanesol about 85% of the activity with undecaprenol Lactiplantibacillus plantarum ADP + solanesyl phosphate
-
 ?
2.7.1.66 ATP + undecaprenol best substrate Lactiplantibacillus plantarum ADP + undecaprenyl monophosphate
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.7.1.66 30 35
-
 Lactiplantibacillus plantarum

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.1.66 7.5 9
-
 Lactiplantibacillus plantarum