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Literature summary extracted from

  • Koizumi, K.; Shimamoto, Y.; Azuma, A.; Wataya, Y.; Matsuda, A.; Sasaki, T.; Fukushima, M.
    Cloning and expression of uridine/cytidine kinase cDNA from human fibrosarcoma cells (2001), Int. J. Mol. Med., 8, 273-278.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.1.48
-
 Mus musculus
2.7.1.48
-
 Escherichia coli
2.7.1.48
-
 Saccharomyces cerevisiae
2.7.1.48 expression in Escherichia coli Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.48 Escherichia coli
-
-
-
2.7.1.48 Homo sapiens
-
-
-
2.7.1.48 Mus musculus
-
-
-
2.7.1.48 Saccharomyces cerevisiae
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.1.48 recombinant His-tagged uridine kinase, Ni-nitrilotriacetic acid-Sepharose Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.48 adenocarcinoma cell SW480 colorectal cells, uridine kinases mRNA expression is higher than in normal tissue Homo sapiens
-
2.7.1.48 bone marrow uridine kinases mRNA expression Homo sapiens
-
2.7.1.48 fibrosarcoma cell
-
 Homo sapiens
-
2.7.1.48 HeLa-S3 cell uridine kinases mRNA expression is higher than in normal tissue Homo sapiens
-
2.7.1.48 kidney uridine kinases mRNA expression Homo sapiens
-
2.7.1.48 large intestine uridine kinases mRNA expression Homo sapiens
-
2.7.1.48 leukemia cell line leukemia cells Hl-60, K562 and Molt-4, uridine kinases mRNA expression is higher than in normal tissue Homo sapiens
-
2.7.1.48 leukocyte peripheral blood leukocyte, uridine kinases mRNA expression Homo sapiens
-
2.7.1.48 liver uridine kinases mRNA expression Homo sapiens
-
2.7.1.48 lung uridine kinases mRNA expression Homo sapiens
-
2.7.1.48 lung cancer cell A549 lung carcinoma cells, uridine kinases mRNA expression is higher than in normal tissue Homo sapiens
-
2.7.1.48 lymph node uridine kinases mRNA expression Homo sapiens
-
2.7.1.48 lymphoma cell Raji and Daud Burkitt's lymphoma cells, uridine kinases mRNA expression is higher than in normal tissue Homo sapiens
-
2.7.1.48 ovary uridine kinases mRNA expression Homo sapiens
-
2.7.1.48 small intestine uridine kinases mRNA expression Homo sapiens
-
2.7.1.48 spleen uridine kinases mRNA expression Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.48 ATP + 3'-deoxy-3'-ethynylcytidine recombinant uridine kinase, 20% of activity with uridine Homo sapiens ADP + 3'-deoxy-3'-ethynylcytidine 5'-monophosphate
-
 ?
2.7.1.48 ATP + 3'-deoxy-3'-ethynyluridine recombinant uridine kinase, 20% of activity with uridine Homo sapiens ADP + 3'-deoxy-3'-ethynyluridine 5'-monophosphate
-
 ?
2.7.1.48 ATP + 5-fluorouridine
-
 Mus musculus ADP + 5-fluorouridine 5'-monophosphate
-
 ?
2.7.1.48 ATP + 5-fluorouridine recombinant uridine kinase Homo sapiens ADP + 5-fluorouridine 5'-monophosphate
-
 ?
2.7.1.48 ATP + cyclopentenylcytosine recombinant uridine kinase, 12% of activity with uridine Homo sapiens ADP + cyclopentenylcytosine 5'-monophosphate
-
 ?
2.7.1.48 ATP + cytidine
-
 Mus musculus ADP + CMP
-
 ?
2.7.1.48 ATP + cytidine
-
 Escherichia coli ADP + CMP
-
 ?
2.7.1.48 ATP + cytidine
-
 Homo sapiens ADP + CMP
-
 ?
2.7.1.48 dATP + cytidine recombinant uridine kinase Homo sapiens dADP + CMP
-
 ?
2.7.1.48 dATP + uridine
-
 Mus musculus dADP + UMP
-
 ?
2.7.1.48 dATP + uridine recombinant uridine kinase Homo sapiens dADP + UMP
-
 ?
2.7.1.48 dCTP + cytidine recombinant uridine kinase Homo sapiens dCDP + CMP
-
 ?
2.7.1.48 dUTP + cytidine recombinant uridine kinase Homo sapiens dUDP + CMP
-
 ?
2.7.1.48 dUTP + uridine
-
 Mus musculus dUDP + UMP
-
 ?
2.7.1.48 dUTP + uridine recombinant uridine kinase Homo sapiens dUDP + UMP
-
 ?