EC Number | Cloned (Comment) | Organism |
---|---|---|
2.7.1.39 | the combination of pTZ19u(ThrB) and the BL21(DE3) cell line is the best expression system with nearly 160 mg of enzyme produced in 4 liters of growth medium | Escherichia coli |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.39 | diethyl dicarbonate | - |
Escherichia coli | |
2.7.1.39 | L-homoserine | substrate inhibition | Escherichia coli | |
2.7.1.39 | pyridoxal 5'-phosphate | - |
Escherichia coli |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.39 | ATP + L-homoserine | Escherichia coli | key enzyme in the aspartate pathway of amino acid biosynthesis in E. coli | ADP + O-phospho-L-homoserine | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.1.39 | Escherichia coli | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.39 | ATP + L-homoserine | - |
Escherichia coli | ADP + O-phospho-L-homoserine | - |
? | |
2.7.1.39 | ATP + L-homoserine | key enzyme in the aspartate pathway of amino acid biosynthesis in E. coli | Escherichia coli | ADP + O-phospho-L-homoserine | - |
? |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.7.1.39 | 6 | 8.5 | - |
Escherichia coli |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.7.1.39 | additional information | - |
additional information | - |
Escherichia coli | |
2.7.1.39 | 0.1 | - |
L-homoserine | in 20% DMSO | Escherichia coli | |
2.7.1.39 | 3 | - |
L-homoserine | aqueous sulution, pH 8 | Escherichia coli |