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Literature summary extracted from

  • Kigoshi, T.; Uchida, K.; Kaneko, M.; Iwasaki, R.; Nakano, S.; Azukizawa, S.; Morimoto, S.
    Direct inhibition of smooth muscle myosin light chain kinase by arachidonic acid in a purified system (1990), Biochem. Biophys. Res. Commun., 171, 369-374.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.11.18 arachidonic acid
-
 Meleagris gallopavo
2.7.11.18 linoleic acid
-
 Meleagris gallopavo
2.7.11.18 additional information no inhibition by diacylglycerol, phosphatidylserine Meleagris gallopavo
2.7.11.18 oleic acid
-
 Meleagris gallopavo
2.7.11.18 unsaturated fatty acids irreversible by Ca2+/calmodulin Meleagris gallopavo

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.11.18 Ca2+
-
 Meleagris gallopavo

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.18 ATP + myosin light chain Meleagris gallopavo
-
 ADP + myosin light chain phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.18 Meleagris gallopavo
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.18 gizzard
-
 Meleagris gallopavo
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.18 ATP + myosin light chain
-
 Meleagris gallopavo ADP + myosin light chain phosphate
-
 ?
2.7.11.18 ATP + myosin light chain acceptor substrates are myosin light chains of smooth muscle myosin Meleagris gallopavo ADP + myosin light chain phosphate
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.11.18 Calmodulin requirement Meleagris gallopavo