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Literature summary extracted from

  • Wang, J.Y.J.; Koshland, D.E.
    The reversible phosphorylation of isocitrate dehydrogenase of Salmonella typhimurium (1982), Arch. Biochem. Biophys., 218, 59-67.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.11.5 2-deoxy-D-glucose
-
 Salmonella enterica subsp. enterica serovar Typhimurium
2.7.11.5 acetate
-
 Salmonella enterica subsp. enterica serovar Typhimurium
2.7.11.5 alpha-methylglucoside
-
 Salmonella enterica subsp. enterica serovar Typhimurium
2.7.11.5 ethanol
-
 Salmonella enterica subsp. enterica serovar Typhimurium

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.11.5 glyoxylate in combination with oxaloacetate Salmonella enterica subsp. enterica serovar Typhimurium
2.7.11.5 oxaloacetate
-
 Salmonella enterica subsp. enterica serovar Typhimurium
2.7.11.5 pyruvate
-
 Salmonella enterica subsp. enterica serovar Typhimurium

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.5 ATP + [isocitrate dehydrogenase (NADP+)] Salmonella enterica subsp. enterica serovar Typhimurium reversible phosphorylation of isocitrate dehydrogenase plays a major role in the control of the Krebs cycle and glyoxylate pathways ADP + [isocitrate dehydrogenase (NADP+)] phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.5 Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.5 ATP + [isocitrate dehydrogenase (NADP+)]
-
 Salmonella enterica subsp. enterica serovar Typhimurium ADP + [isocitrate dehydrogenase (NADP+)] phosphate
-
 ?
2.7.11.5 ATP + [isocitrate dehydrogenase (NADP+)] reversible phosphorylation of isocitrate dehydrogenase plays a major role in the control of the Krebs cycle and glyoxylate pathways Salmonella enterica subsp. enterica serovar Typhimurium ADP + [isocitrate dehydrogenase (NADP+)] phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.11.5 IDH kinase
-
 Salmonella enterica subsp. enterica serovar Typhimurium