EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.1 | D-glucose 6-phosphate | marked inhibition of particulate hexokinase I activity | Lithobates catesbeianus | |
2.7.1.1 | GSSG | product inhibition | Lithobates catesbeianus | |
2.7.1.1 | additional information | not inhibited by 2-deoxy-D-glucose 6-phosphate | Lithobates catesbeianus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.7.1.1 | 0.14 | - |
D-glucose | - |
Lithobates catesbeianus | |
2.7.1.1 | 3.6 | - |
2-deoxy-D-glucose | - |
Lithobates catesbeianus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.7.1.1 | particle-bound | 73% of the activity in retinas is associated with the particulate fraction and 27% with the soluble fraction | Lithobates catesbeianus | - |
- |
2.7.1.1 | soluble | 73% of the activity in retinas is associated with the particulate fraction and 27% with the soluble fraction | Lithobates catesbeianus | - |
- |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.1.1 | Lithobates catesbeianus | - |
bullfrog, hexokinase I | - |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.1.1 | retina | - |
Lithobates catesbeianus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.1 | ATP + 2-deoxy-D-glucose | - |
Lithobates catesbeianus | ADP + 2-deoxy-D-glucose 6-phosphate | - |
? | |
2.7.1.1 | D-fructose + ATP | - |
Lithobates catesbeianus | ADP + D-fructose 6-phosphate | - |
? | |
2.7.1.1 | D-glucose + ATP | - |
Lithobates catesbeianus | ADP + D-glucose 6-phosphate | - |
? | |
2.7.1.1 | D-mannose + ATP | - |
Lithobates catesbeianus | ADP + D-mannose 6-phosphate | - |
? | |
2.7.1.1 | additional information | not: D-galactose | Lithobates catesbeianus | ? | - |
? |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.1 | AMP | much less stimulation than by cAMP | Lithobates catesbeianus | |
2.7.1.1 | ATP | - |
Lithobates catesbeianus | |
2.7.1.1 | cAMP | stimulates, 0.2-0.8 mM: 2fold | Lithobates catesbeianus |