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Literature summary extracted from

  • Taylor, R.T.; Jenkins, W.T.
    Leucine aminotransferase. 3. Activation by beta-mercaptoethanol (1966), J. Biol. Chem., 241, 4406-4410.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.6.1.42 2-mercaptoethanol
-
 Sus scrofa

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.6.1.42 cupric acetate
-
 Sus scrofa
2.6.1.42 HgCl2
-
 Sus scrofa
2.6.1.42 Lead acetate
-
 Sus scrofa
2.6.1.42 additional information less than 10% inhibition with iodoacetamide, iodoacetate, sodium arsenite, oxidized glutathione, potassium ferricyanide, stannous chloride, ceric sulfate, aluminium chloride, cobalt chloride, ferric chloride, manganese chloride, magnesium chloride, calcium chloride or ferrous ammonium sulfate Sus scrofa
2.6.1.42 N-ethylmaleimide
-
 Sus scrofa
2.6.1.42 p-chloromercuribenzoate
-
 Sus scrofa
2.6.1.42 silver acetate
-
 Sus scrofa
2.6.1.42 Sodium mersalyl
-
 Sus scrofa
2.6.1.42 Zinc acetate
-
 Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.42 Sus scrofa
-
 pig, hog
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.6.1.42
-
 Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.6.1.42 heart
-
 Sus scrofa
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.6.1.42 25.3
-
 in presence of 2-mercaptoethanol Sus scrofa

Storage Stability

EC Number Storage Stability Organism
2.6.1.42 5°C, remarkably stable in crude extract when stored in 0.05 M sodium caproate, 0.5 mM EDTA, pH 6.1, no loss of activity after 1 month Sus scrofa
2.6.1.42 5°C, stored in 0.05 M sodium diphosphate, 0.1 M 2-mercaptoethanol, pH 8.5, loses about 50% activity over a period of several days Sus scrofa

Synonyms

EC Number Synonyms Comment Organism
2.6.1.42 leucine aminotransferase
-
 Sus scrofa