EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.6.1.31 | arsenate | activation, less effective than phosphate | Rattus norvegicus | |
2.6.1.31 | D-Aspartate | increases activity | Rattus norvegicus | |
2.6.1.31 | diphosphate | activation, less effective than phosphate | Rattus norvegicus | |
2.6.1.31 | phosphate | essential, activation in absence of diethylstilbestrol and pyridoxal 5'-phosphate | Rattus norvegicus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.6.1.31 | 2-oxoglutarate | inhibition at pH 7.0 is higher than at pH 8.5, 3.33 mM in presence of equimolar concentrations of oxaloacetate | Rattus norvegicus | |
2.6.1.31 | 2-Oxomalonate | inhibition at pH 7.0 is higher than at pH 8.5, 0.4 mM in presence of equimolar concentrations of oxaloacetate | Rattus norvegicus | |
2.6.1.31 | 3,3-Dimethylglutamic acid | not at pH 7.0, weak at pH 8.0 | Rattus norvegicus | |
2.6.1.31 | 3-oxoadipate | inhibition at pH 7.0 is higher than at pH 8.5, 3.33 mM in presence of equimolar concentrations of oxaloacetate | Rattus norvegicus | |
2.6.1.31 | adipic acid | not at pH 7.0, weak at pH 8.0 | Rattus norvegicus | |
2.6.1.31 | Benzylmalonic acid | not at pH 7.0, weak at pH 8.0 | Rattus norvegicus | |
2.6.1.31 | Diethylstilbestrol diphosphate | - |
Rattus norvegicus | |
2.6.1.31 | L-aspartate | - |
Rattus norvegicus | |
2.6.1.31 | L-glutamate | - |
Rattus norvegicus | |
2.6.1.31 | pyridoxal 5'-phosphate | - |
Rattus norvegicus | |
2.6.1.31 | pyridoxamine phosphate | - |
Rattus norvegicus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.6.1.31 | 0.012 | - |
oxaloacetate | somewhat higher at very high levels of pyridoxamine, 14 mM | Rattus norvegicus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.6.1.31 | pyridoxamine + oxaloacetate | Rattus norvegicus | - |
pyridoxal + L-aspartate | - |
r |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.6.1.31 | Rattus norvegicus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.6.1.31 | 979fold | Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.6.1.31 | kidney | - |
Rattus norvegicus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.6.1.31 | 0.066 | - |
purified enzyme | Rattus norvegicus |
EC Number | Storage Stability | Organism |
---|---|---|
2.6.1.31 | frozen, 20% loss of activity after 2 months | Rattus norvegicus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.6.1.31 | pyridoxamine + oxaloacetate | - |
Rattus norvegicus | pyridoxal + L-aspartate | - |
r |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.6.1.31 | 8.5 | - |
- |
Rattus norvegicus |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
2.6.1.31 | 7.5 | 9.5 | about 50% of activity maximum at pH 7.5 and pH 9.5 | Rattus norvegicus |