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Literature summary extracted from

  • Stuart, F.; Hunter, I.S.
    Purification and characterisation of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Streptomyces rimosus (1993), Biochim. Biophys. Acta, 1161, 209-215.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.5.1.54 Trp Trp-sensitive isozyme Streptomyces rimosus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.5.1.54 0.0026
-
 D-erythrose 4-phosphate pH 7.0, 37°C Streptomyces rimosus
2.5.1.54 0.0067
-
 phosphoenolpyruvate pH 7.0, 37°C Streptomyces rimosus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.5.1.54 59000
-
 2 * 59000, SDS-PAGE Streptomyces rimosus
2.5.1.54 120000
-
 gel filtration Streptomyces rimosus

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.54 Streptomyces rimosus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.5.1.54 2700fold Streptomyces rimosus

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.5.1.54 7.8
-
 purified enzyme Streptomyces rimosus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.54 phosphoenolpyruvate + D-erythrose 4-phosphate + H2O
-
 Streptomyces rimosus 2-dehydro-3-deoxy-D-arabino-heptonate 7-phosphate + phosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
2.5.1.54 dimer 2 * 59000, SDS-PAGE Streptomyces rimosus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.5.1.54 37
-
 assay at Streptomyces rimosus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.5.1.54 7
-
-
 Streptomyces rimosus