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Literature summary extracted from

  • Stephens, C.M.; Bauerle, R.
    Analysis of the metal requirement of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Escherichia coli (1991), J. Biol. Chem., 266, 20810-20817.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.5.1.54 overexpression of 3 isozymes Escherichia coli

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.5.1.54 EDTA reversible by diverse divalent metal ions with varying efficiency Escherichia coli
2.5.1.54 Phe feed-back inhibition, Phe-sensitive isozyme; Phe-sensitive isozyme Escherichia coli

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.5.1.54 Cu2+ 3 isozymes contain traces of Cu2+ Escherichia coli
2.5.1.54 Fe2+ stimulates Escherichia coli
2.5.1.54 Fe2+ the 3 isozymes contain 0.2-0.3 mol of iron per mol of enzyme monomer Escherichia coli
2.5.1.54 Zn2+ 3 isozymes contain variable amounts of zinc Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.54 Escherichia coli
-
 3 isoenzymes
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.5.1.54 recombinant from overexpressing strain Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.54 phosphoenolpyruvate + D-erythrose 4-phosphate + H2O
-
 Escherichia coli 2-dehydro-3-deoxy-D-arabino-heptonate 7-phosphate + phosphate
-
 ?