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Literature summary extracted from

  • Sauer, F.D.
    Tetrahydromethanopterin methyltransferase, a component of the methane synthesizing complex of Methanobacterium thermoautotrophicum (1986), Biochem. Biophys. Res. Commun., 136, 542-547.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.1.1.86 0.88
-
 5,6,7,8-tetrahydromethanopterin
-
 Methanothermobacter thermautotrophicus
2.1.1.86 3.7
-
 (2-methylthio)ethanesulfonate
-
 Methanothermobacter thermautotrophicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.1.1.86 5-methyl-5,6,7,8-tetrahydromethanopterin + 2-mercaptoethanesulfonate Methanothermobacter thermautotrophicus involved in the formation of methane from CO 5,6,7,8-tetrahydromethanopterin + 2-(methylthio)ethanesulfonate
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.86 Methanothermobacter thermautotrophicus
-
-
-

Oxidation Stability

EC Number Oxidation Stability Organism
2.1.1.86 oxygen-sensitive Methanothermobacter thermautotrophicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.86 5-methyl-5,6,7,8-tetrahydromethanopterin + 2-mercaptoethanesulfonate
-
 Methanothermobacter thermautotrophicus 5,6,7,8-tetrahydromethanopterin + 2-(methylthio)ethanesulfonate
-
 r
2.1.1.86 5-methyl-5,6,7,8-tetrahydromethanopterin + 2-mercaptoethanesulfonate involved in the formation of methane from CO Methanothermobacter thermautotrophicus 5,6,7,8-tetrahydromethanopterin + 2-(methylthio)ethanesulfonate
-
 r

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.1.1.86 60
-
 assay at Methanothermobacter thermautotrophicus

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
2.1.1.86 100
-
 5 min, inactivation Methanothermobacter thermautotrophicus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.1.1.86 6.7
-
-
 Methanothermobacter thermautotrophicus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.1.1.86 6 7 sharp decrease in activity below pH 6.0 and above pH 7.0 Methanothermobacter thermautotrophicus