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Literature summary extracted from

  • Rohdich, F.; Zepeck, F.; Adam, P.; Hecht, S.; Kaiser, J.; Laupitz, R.; Grawert, T.; Amslinger, S.; Eisenreich, W.; Bacher, A.; Arigoni, D.
    The deoxyxylulose phosphate pathway of isoprenoid biosynthesis: Studies on the mechanisms of the reactions catalyzed by IspG and isph protein (2003), Proc. Natl. Acad. Sci. USA, 100, 1586-1591.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.17.7.3 recombinant fusion protein comprising maltose binding protein and IspG protein domains is expressed in Escherichia coli Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.17.7.3 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + reduced flavodoxin Escherichia coli the enzyme is involved in the deoxyxylulose phosphate pathway of isoprenoid biosynthesis (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H2O + oxidized flavodoxin
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 ?

Organism

EC Number Organism UniProt Comment Textmining
1.17.7.3 Escherichia coli P62620
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Purification (Commentary)

EC Number Purification (Comment) Organism
1.17.7.3 recombinant fusion protein comprising maltose binding protein and IspG protein domains Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.17.7.3 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + reduced 10-methyl-5-deazaisoalloxazine
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 Escherichia coli (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H2O + oxidized 10-methyl-5-deazaisoalloxazine
-
 ?
1.17.7.3 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + reduced flavodoxin the enzyme is involved in the deoxyxylulose phosphate pathway of isoprenoid biosynthesis Escherichia coli (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H2O + oxidized flavodoxin
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.17.7.3 IspG ambiguous Escherichia coli

General Information

EC Number General Information Comment Organism
1.17.7.3 metabolism the enzyme is involved in the deoxyxylulose phosphate pathway of isoprenoid biosynthesis Escherichia coli