Literature summary extracted from

MacMillan, D.K.; Hill, E.; Sala, A.; Sigal, E.; Shuman, T.; Henson, P.M.; Murphy, R.C.
Eosinophil 15-lipoxygenase is a leukotriene A4 synthase (1994), J. Biol. Chem., 269, 26663-26668.

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.13.11.33	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.13.11.33	eosinophil	eosinophil 15-lipoxygenase is a leukotriene A4 synthase	Homo sapiens	-
1.13.11.33	neutrophil	neutrophils do not express 15-lipoxygenase	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.13.11.33	arachidonate + O2	-	Homo sapiens	(5Z,8Z,11Z,13E)-(15S)-15-hydroperoxyeicosa-5,8,11,13-tetraenoate	-	?

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Release 2023.1 (January 2023)