Literature summary extracted from

Sigal, E.; Grunberger, D.; Highland, E.; Gross, C.; Dixon, R.A.F.; Craik, C.S.
Expression of cloned human reticulocyte 15-lipoxygenase and immunological evidence that 15-lipoxygenases of different cell types are related (1990), J. Biol. Chem., 265, 5113-5120.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
1.13.11.33	expression in a human osteosarcoma cell line, expression of a CheY-15-lipoxygenase fusion protein in Escherichia coli	Homo sapiens

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.13.11.33	5,8,11,14-Eicosatetraynoic acid	-	Homo sapiens
1.13.11.33	eicosatetraynoic acid	-	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.13.11.33	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.13.11.33	reticulocyte	-	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.13.11.33	arachidonate + O2	-	Homo sapiens	(5Z,8Z,11Z,13E)-(15S)-15-hydroperoxyeicosa-5,8,11,13-tetraenoate	15-hydroxyeicosatetraenoic acid and 12-hydroxyeicosatetraenoic acid in a ratio of 8.6:1	?
1.13.11.33	linoleic acid + O2	-	Homo sapiens	13-hydroxylinoleic acid	-	?

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Release 2023.1 (January 2023)