EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.1.1.78 | 2,2'-dithiodipyridine | - |
Rauvolfia serpentina Benth. ex Kurz | |
3.1.1.78 | 5,5'-dithio-bis-(2-nitrobenzoate) | - |
Rauvolfia serpentina Benth. ex Kurz | |
3.1.1.78 | iodoacetamide | 100% inhibition at 5 mM | Rauvolfia serpentina Benth. ex Kurz | |
3.1.1.78 | MgCl2 | 50% inhibition at 0.25 mM | Rauvolfia serpentina Benth. ex Kurz | |
3.1.1.78 | MnCl2 | 50% inhibition at 0.25 mM | Rauvolfia serpentina Benth. ex Kurz | |
3.1.1.78 | ZnCl2 | 50% inhibition at 0.25 mM | Rauvolfia serpentina Benth. ex Kurz |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.1.1.78 | 1.25 | - |
polyneuridine aldehyde | - |
Rauvolfia serpentina Benth. ex Kurz |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.1.78 | polyneuridine aldehyde + H2O | Rauvolfia serpentina Benth. ex Kurz | key enzyme in the biosynthesis of sarpagine/ajmaline type alkaloids | 16-epivellosimine + CO2 + methanol | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.1.78 | Rauvolfia serpentina Benth. ex Kurz | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.1.1.78 | - |
Rauvolfia serpentina Benth. ex Kurz |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|
EC Number | Storage Stability | Organism |
---|---|---|
3.1.1.78 | 0°C, 5 months, 0.2 M 2-mercaptoethanol, 100% activity | Rauvolfia serpentina Benth. ex Kurz |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.1.78 | akuammidine aldehyde + H2O | - |
Rauvolfia serpentina Benth. ex Kurz | vellosiminol + CO2 + methanol | - |
? | |
3.1.1.78 | polyneuridine aldehyde + H2O | - |
Rauvolfia serpentina Benth. ex Kurz | 16-epivellosimine + CO2 + methanol | - |
? | |
3.1.1.78 | polyneuridine aldehyde + H2O | key enzyme in the biosynthesis of sarpagine/ajmaline type alkaloids | Rauvolfia serpentina Benth. ex Kurz | 16-epivellosimine + CO2 + methanol | - |
? |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.1.1.78 | 6.5 | - |
- |
Rauvolfia serpentina Benth. ex Kurz |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
3.1.1.78 | 4 | 8.5 | - |
Rauvolfia serpentina Benth. ex Kurz |