Literature summary extracted from

Parker, A.; Gockerman, A.; Busby, W.H.; Clemmons, D.R.
Properties of an insulin-like growth factor-binding protein-4 protease that is secreted by smooth muscle cells (1995), Endocrinology, 136, 2470-2476.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.4.24.79	1,10-phenanthroline	-	Sus scrofa
3.4.24.79	3,4-dichloroisocoumarin	-	Sus scrofa
3.4.24.79	alpha1-Aantichymotrypsin	potent inhibitor	Sus scrofa
3.4.24.79	EDTA	-	Sus scrofa
3.4.24.79	heparin	up to 60% inhibition	Sus scrofa

Metals/Ions

EC Number	Metals/Ions	Comment	Organism	Structure
3.4.24.79	Ca2+	-	Sus scrofa

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.24.79	Sus scrofa	-	-	-

Renatured (Commentary)

EC Number	Renatured (Comment)	Organism
3.4.24.79	readdition of 5 mM Ca2+, but not of 0.1 mM Zn2+, restores EDTA-treated enzyme	Sus scrofa

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.4.24.79	smooth muscle	-	Sus scrofa	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.4.24.79	additional information	serine protease	Sus scrofa	?	-	?

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)