Literature summary extracted from

Sun, I.Y.C.; Overgaard, M.T.; Oxvig, C.; Giudice, L.C.
Pregnancy-associated plasma protein A proteolytic activity is associated with the human placental trophoblast cell membrane (2002), J. Clin. Endocrinol. Metab., 87, 5235-5240.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
3.4.24.79	IGF	PAPP-A activity is dependent on presence of insulin-like growth factor-II	Homo sapiens

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.4.24.79	EDTA	5 mM	Homo sapiens
3.4.24.79	EGTA	5 mM	Homo sapiens

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.24.79	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.4.24.79	decidua	-	Homo sapiens	-
3.4.24.79	placenta	-	Homo sapiens	-
3.4.24.79	trophoblast	-	Homo sapiens	-

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Release 2023.1 (January 2023)