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Literature summary extracted from
- Effect of proteinase inhibitors on intracellular processing of cathepsin B, H and L in rat macrophages (1988), FEBS Lett., 231, 229-231.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.22.16 | additional information | metalloendopeptidases involved in processing of procathepsin to active enzyme | Rattus norvegicus |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.22.16 | 1,10-phenanthroline | inhibits processing of proenzyme to active form | Rattus norvegicus |  |
| 3.4.22.16 | benzyloxycarbonyl-Gly-Leu-NH | inhibits processing of proenzyme to active form | Rattus norvegicus | |
| 3.4.22.16 | Benzyloxycarbonyl-Leu-NH2 | inhibits formation of active enzyme from procathepsin H | Rattus norvegicus | |
| 3.4.22.16 | ethyl(2S,3S)-3-(S)-3-methyl-1-(3-methylbutylcarbamoyl)butylcarbamoyl oxirane-2-carboxylate | E-64-d, inhibits processing of proenzyme to active form | Rattus norvegicus | |
| 3.4.22.16 | leupeptin | inhibits processing of proenzyme to active form | Rattus norvegicus | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.22.16 | Rattus norvegicus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.22.16 | macrophage | - |
Rattus norvegicus | - |
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Release 2023.1 (January 2023)
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