BRENDA - Enzyme Database show

Cloning and molecular expression analysis of large and small lecithin:retinol acyltransferase mRNAs in the liver and other tissues of adult rats

Zolfaghari, R.; Wang, Y.; Chen, Q.; Sancher, A.; Ross, A.C.; Biochem. J. 368, 621-631 (2002)

Data extracted from this reference:

Activating Compound
EC Number
Activating Compound
Commentary
Organism
Structure
2.3.1.135
additional information
activation and mRNA expression for LRAT is blocked completely in vivo by actinomycin D; retinoic acid must be continuously present to maintain LRAT gene expression in the ON position
Rattus norvegicus
2.3.1.135
retinoic acid
minimal dose for significant increase in LRAT activity and mRNA expression: 0.005 mg
Rattus norvegicus
Cloned(Commentary)
EC Number
Commentary
Organism
2.3.1.135
expression in HEK-293T cells
Rattus norvegicus
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.3.1.135
Rattus norvegicus
Q9JI61
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.3.1.135
liver
-
Rattus norvegicus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.3.1.135
phosphatidylcholine + retinol-(cellular-retinol-binding-protein)
-
638624
Rattus norvegicus
2-acylglycerophosphocholine + retinyl ester-(cellular-retinol-binding-protein)
-
638624
Rattus norvegicus
?
Activating Compound (protein specific)
EC Number
Activating Compound
Commentary
Organism
Structure
2.3.1.135
additional information
activation and mRNA expression for LRAT is blocked completely in vivo by actinomycin D; retinoic acid must be continuously present to maintain LRAT gene expression in the ON position
Rattus norvegicus
2.3.1.135
retinoic acid
minimal dose for significant increase in LRAT activity and mRNA expression: 0.005 mg
Rattus norvegicus
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
2.3.1.135
expression in HEK-293T cells
Rattus norvegicus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.3.1.135
liver
-
Rattus norvegicus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.3.1.135
phosphatidylcholine + retinol-(cellular-retinol-binding-protein)
-
638624
Rattus norvegicus
2-acylglycerophosphocholine + retinyl ester-(cellular-retinol-binding-protein)
-
638624
Rattus norvegicus
?