Literature summary extracted from

Guo, X.; Knudsen, B.S.; Peehl, D.M.; Ruiz, A.; Bok, D.; Rando, R.R.; Rhim, J.S.; Nanus, D.M.; Gudas, L.J.
Retinol metabolism and lecithin:retinol acyltransferase levels are reduced in cultured human prostate cancer cells and tissue specimens (2002), Cancer Res., 62, 1654-1661.

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.3.1.135	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.3.1.135	breast adenocarcinoma cell	breast carcinoma cells have lower LRAT activity	Homo sapiens	-
2.3.1.135	carcinoma cell	skin, these cells have lower LRAT activity	Homo sapiens	-
2.3.1.135	prostate	practically no activity in prostatic cancer cells	Homo sapiens	-
2.3.1.135	prostate cancer cell	adenocarcinoma, LRAT is downregulated as a result of oncogenic transformation	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.3.1.135	phosphatidylcholine + all-trans-retinol	-	Homo sapiens	all-trans-retinyl acyl esters + 2-acylglycerophosphocholine	-	r

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Release 2023.1 (January 2023)