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Retinol esterification in bovine retinal pigment epithelium: reversibility of lecithin:retinol acyltransferase

Saari, J.C.; Bredberg, D.L.; Farrell, D.F.; Biochem. J. 291, 697-700 (1993)
No PubMed abstract available

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
2.3.1.135
additional information
1-acyl-lysophosphatidylcholine does not inhibit LRAT up to 0.020 mM; product inhibition by retinyl ester can be ruled out
Bos taurus
KM Value [mM]
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
2.3.1.135
0.0042
-
all-trans-retinol
reaction with phosphatidylcholine
Bos taurus
2.3.1.135
0.006
-
11-cis-retinol
reaction with phosphatidylcholine
Bos taurus
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.3.1.135
Bos taurus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.3.1.135
retinal pigment epithelium
-
Bos taurus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.3.1.135
phosphatidylcholine + 11-cis-retinol
-
638615
Bos taurus
11-cis-retinyl acyl ester + 2-acylglycerophosphocholine
-
638615
Bos taurus
r
2.3.1.135
phosphatidylcholine + all-trans-retinol
-
638615
Bos taurus
all-trans-retinyl acyl esters + 2-acylglycerophosphocholine
-
638615
Bos taurus
r
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
2.3.1.135
additional information
1-acyl-lysophosphatidylcholine does not inhibit LRAT up to 0.020 mM; product inhibition by retinyl ester can be ruled out
Bos taurus
KM Value [mM] (protein specific)
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
2.3.1.135
0.0042
-
all-trans-retinol
reaction with phosphatidylcholine
Bos taurus
2.3.1.135
0.006
-
11-cis-retinol
reaction with phosphatidylcholine
Bos taurus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.3.1.135
retinal pigment epithelium
-
Bos taurus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.3.1.135
phosphatidylcholine + 11-cis-retinol
-
638615
Bos taurus
11-cis-retinyl acyl ester + 2-acylglycerophosphocholine
-
638615
Bos taurus
r
2.3.1.135
phosphatidylcholine + all-trans-retinol
-
638615
Bos taurus
all-trans-retinyl acyl esters + 2-acylglycerophosphocholine
-
638615
Bos taurus
r