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Literature summary extracted from

  • MacDonald, P.N.; Ong, D.E.
    A lecithin:retinol acyltransferase activity in human and rat liver (1988), Biochem. Biophys. Res. Commun., 156, 157-163.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.135 N-ethylmaleimide 0.001 mM, complete inhibition of retinol-(cellular-retinol-binding-protein)type II esterification Homo sapiens
2.3.1.135 N-ethylmaleimide
-
 Rattus norvegicus
2.3.1.135 phenylmethylsulfonyl fluoride 2 mM, 90% inhibition of retinol-(cellular-retinol-binding-protein)type II esterification Homo sapiens
2.3.1.135 phenylmethylsulfonyl fluoride
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.135 0.0005
-
 retinol-(cellular-retinol-binding-protein) reaction with phosphatidylcholine Homo sapiens
2.3.1.135 0.001
-
 retinol-[cellular-retinol-binding-protein] liver LRAT, reaction with phosphatidylcholine Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.135 microsome
-
 Homo sapiens
-
-
2.3.1.135 microsome
-
 Rattus norvegicus
-
-

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.135 Homo sapiens
-
-
-
2.3.1.135 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.135 liver
-
 Homo sapiens
-
2.3.1.135 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.135 additional information little or no ability to transfer acyl groups from lysophosphatidylcholine, phosphatidylethanolamine or phosphatidic acid to retinol-(cellular-retinol-binding protein) Homo sapiens ?
-
 ?
2.3.1.135 additional information little or no ability to transfer acyl groups from lysophosphatidylcholine, phosphatidylethanolamine or phosphatidic acid to retinol-(cellular-retinol-binding protein) Rattus norvegicus ?
-
 ?
2.3.1.135 additional information only fatty acyl group at the sn-1 is transferred Homo sapiens ?
-
 ?
2.3.1.135 additional information only fatty acyl group at the sn-1 is transferred Rattus norvegicus ?
-
 ?
2.3.1.135 additional information phosphatidylcholine selective Homo sapiens ?
-
 ?
2.3.1.135 additional information phosphatidylcholine selective Rattus norvegicus ?
-
 ?
2.3.1.135 phosphatidylcholine + retinol-(cellular-retinol-binding-protein)
-
 Homo sapiens 2-acylglycerophosphocholine + retinyl ester-(cellular-retinol-binding-protein)
-
 ?
2.3.1.135 phosphatidylcholine + retinol-(cellular-retinol-binding-protein)
-
 Rattus norvegicus 2-acylglycerophosphocholine + retinyl ester-(cellular-retinol-binding-protein)
-
 ?
2.3.1.135 phosphatidylcholine + retinol-[cellular-retinol-binding-protein]
-
 Rattus norvegicus 2-acylglycerophosphocholine + retinyl-ester-[cellular-retinol-binding-protein]
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.135 37
-
-
 Homo sapiens
2.3.1.135 37
-
-
 Rattus norvegicus